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ChEBI
> Main
CHEBI:74767 - Pro-Hyp
Main
ChEBI Ontology
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ChEBI Name
Pro-Hyp
ChEBI ID
CHEBI:74767
Definition
A dipeptide composed of
L
-proline and
L
-hydroxyproline residues. It is a biomarker for bone collagen degradation.
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:74516
Supplier Information
Download
Molfile
XML
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Molfile
Formula
C10H16N2O4
Net Charge
0
Average Mass
228.24500
Monoisotopic Mass
228.11101
InChI
InChI=1S/C10H16N2O4/c13-
6-
4-
8(10(15)
16)
12(5-
6)
9(14)
7-
2-
1-
3-
11-
7/h6-
8,11,13H,1-
5H2,(H,15,16)
/t6-
,7+,8+/m1/s1
InChIKey
ONPXCLZMBSJLSP-CSMHCCOUSA-N
SMILES
O[C@@H]1C[C@H](N(C1)C(=O)[C@@H]1CCCN1)C(O)=O
Metabolite of Species
Details
Homo sapiens
(NCBI:txid9606)
See:
PubMed
Roles Classification
Chemical Role
(s):
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Br
o
nsted acid).
(via
organic amino compound
)
Biological Role
(s):
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (
Homo sapiens
).
Application
(s):
diagnostic agent
A substance administered to aid diagnosis of a disease.
biomarker
A substance used as an indicator of a biological state.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
Pro-Hyp (
CHEBI:74767
)
has functional parent
trans
-4-hydroxy-
L
-proline (
CHEBI:18095
)
Pro-Hyp (
CHEBI:74767
)
has functional parent
L
-proline (
CHEBI:17203
)
Pro-Hyp (
CHEBI:74767
)
has role
biomarker (
CHEBI:59163
)
Pro-Hyp (
CHEBI:74767
)
has role
diagnostic agent (
CHEBI:33295
)
Pro-Hyp (
CHEBI:74767
)
has role
human metabolite (
CHEBI:77746
)
Pro-Hyp (
CHEBI:74767
)
is a
dipeptide (
CHEBI:46761
)
Pro-Hyp (
CHEBI:74767
)
is tautomer of
Pro-Hyp zwitterion (
CHEBI:133733
)
Incoming
Pro-Hyp zwitterion (
CHEBI:133733
)
is tautomer of
Pro-Hyp (
CHEBI:74767
)
IUPAC Name
L
-prolyl-(4
R
)-4-hydroxy-
L
-proline
Synonyms
Sources
L
-Pro-
L
-Hyp
ChEBI
L-Prolyl-L-hydroxyproline
HMDB
Prolylhydroxyproline
HMDB
Manual Xref
Database
HMDB0006695
HMDB
View more database links
Registry Numbers
Types
Sources
18684-24-7
CAS Registry Number
HMDB
21943
Reaxys Registry Number
Reaxys
Citations
Types
Sources
12636053
PubMed citation
Europe PMC
22382331
PubMed citation
Europe PMC
Last Modified
13 October 2016