CHEBI:50190 - deptropine citrate

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ChEBI Name deptropine citrate
ChEBI ID CHEBI:50190
Definition A citrate salt that is the dihydrogen citrate salt of deptropamine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formulae C23H27NO.C6H8O7
C29H35NO8
Net Charge 0
Average Mass 525.59010
Monoisotopic Mass 525.23627
InChI InChI=1S/C23H27NO.C6H8O7/c1-24-18-12-13-19(24)15-20(14-18)25-23-21-8-4-2-6-16(21)10-11-17-7-3-5-9-22(17)23;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-9,18-20,23H,10-15H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t18-,19+,20+;
InChIKey CHQGYMXXKZPWOI-BWSPSPBFSA-N
SMILES OC(=O)CC(O)(CC(O)=O)C(O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC1c2ccccc2CCc2ccccc12
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing deptropine citrate (CHEBI:50190) has part deptropine (CHEBI:50189)
deptropine citrate (CHEBI:50190) has role H1-receptor antagonist (CHEBI:37955)
deptropine citrate (CHEBI:50190) has role muscarinic antagonist (CHEBI:48876)
deptropine citrate (CHEBI:50190) has role parasympatholytic (CHEBI:50370)
deptropine citrate (CHEBI:50190) is a citrate salt (CHEBI:50744)
IUPAC Name
(3-endo)-3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yloxy)-8-methyl-8-azabicyclo[3.2.1]octane 2-hydroxypropane-1,2,3-tricarboxylate
Synonyms Sources
Brontina ChemIDplus
Deptrin ChemIDplus
deptropine dihydrogen citrate ChemIDplus
Dibenzheptropine citrate ChemIDplus
Brand Name Source
Deptropine FNA KEGG DRUG
Manual Xref Database
D07790 KEGG DRUG
View more database links
Registry Numbers Types Sources
2169-75-7 CAS Registry Number ChemIDplus
4106261 Reaxys Registry Number Reaxys
4106261 Beilstein Registry Number Beilstein
Last Modified
09 May 2011
General Comment
2011-05-09 A sedating antihistamine with antimuscarinic properties, deptropine citrate was used in the treatment of respiratory tract disorders.