ficellomycin (CHEBI:156531)

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This entity has been annotated by a third party. If you would like more information added to this entry, please contact ChEBI via email or GitHub.

ChEBI Name	ficellomycin

ChEBI ID	CHEBI:156531

Definition	A dipeptide antibiotic containing an azabicyclohexane ring system that exhibits potent in vitro activity against Penicillium oxalicum and Staphylococcus aureus. It inhibits semi-conservative DNA replication by causing accumulation of 34S DNA species.

Stars	This entity has been manually annotated by a third party.

Submitter	Martin Larralde

Supplier Information

Download	Molfile XML SDF

Formula

C13H24N6O3

Net Charge

Average Mass

312.374

Monoisotopic Mass

312.19099

InChI

InChI=1S/C13H24N6O3/c1-5(2)9(14)11(20)18-10(12(21)22)7-3-6(17-13(15)16)8-4-19(7)8/h5-10H,3-4,14H2,1-2H3,(H,18,20)(H,21,22)(H4,15,16,17)

InChIKey

DGIHWRUPUISVIZ-UHFFFAOYSA-N

SMILES

CC(C)C(C(=O)NC(C1CC(C2N1C2)NC(N)=N)C(=O)O)N

Metabolite of Species	Details
Streptomyces ficellus (NCBI:txid1977088)	of strain NRRL8067 See: PubMed

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA. bacterial metabolite Any prokaryotic metabolite produced during a metabolic reaction in bacteria. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. (via alkaloid )

ChEBI Ontology
Outgoing	ficellomycin (CHEBI:156531) has part L-valine (CHEBI:16414) ficellomycin (CHEBI:156531) has part guanidino group (CHEBI:48551) ficellomycin (CHEBI:156531) has role antibacterial agent (CHEBI:33282) ficellomycin (CHEBI:156531) has role bacterial metabolite (CHEBI:76969) ficellomycin (CHEBI:156531) has role DNA synthesis inhibitor (CHEBI:59517) ficellomycin (CHEBI:156531) is a alkaloid (CHEBI:22315) ficellomycin (CHEBI:156531) is a aziridines (CHEBI:22681) ficellomycin (CHEBI:156531) is a dipeptide (CHEBI:46761) ficellomycin (CHEBI:156531) is a pyrrolidines (CHEBI:38260)