CHEBI:131351 - CGS 15943

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ChEBI Name CGS 15943 ChEBI ID CHEBI:131351 Definition A member of the class of triazoloquinazolines that is [1,2,4]triazolo[1,5-c]quinazoline substited at positions 2, 5 and 9 by furan-2-yl, amino and chloro groups respectively. A potent antagonist at adenosine A1 and adenosine A2A receptors. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C13H8ClN5O Net Charge 0 Average Mass 285.689 Monoisotopic Mass 285.04174 InChI InChI=1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16) InChIKey MSJODEOZODDVGW-UHFFFAOYSA-N SMILES N=1C2=C(C=3N(C1N)N=C(N3)C=4OC=CC4)C=C(C=C2)Cl Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): adenosine A1 receptor antagonist An antagonist at the A1 receptor. adenosine A2A receptor antagonist An antagonist at the A2A receptor. Application(s): central nervous system stimulant Any drug that enhances the activity of the central nervous system. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. View more via ChEBI Ontology ChEBI Ontology Outgoing CGS 15943 (CHEBI:131351) has role adenosine A1 receptor antagonist (CHEBI:63957) CGS 15943 (CHEBI:131351) has role adenosine A2A receptor antagonist (CHEBI:53121) CGS 15943 (CHEBI:131351) has role antineoplastic agent (CHEBI:35610) CGS 15943 (CHEBI:131351) has role central nervous system stimulant (CHEBI:35337) CGS 15943 (CHEBI:131351) is a aromatic amine (CHEBI:33860) CGS 15943 (CHEBI:131351) is a biaryl (CHEBI:64459) CGS 15943 (CHEBI:131351) is a furans (CHEBI:24129) CGS 15943 (CHEBI:131351) is a organochlorine compound (CHEBI:36683) CGS 15943 (CHEBI:131351) is a primary amino compound (CHEBI:50994) CGS 15943 (CHEBI:131351) is a triazoloquinazoline (CHEBI:131355) IUPAC Name 9-chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine Synonyms Sources 9-Chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine ChemIDplus CGS 15943A ChemIDplus CGS-15943 ChEBI CGS15943 ChEBI Manual Xref Database CGS-15943 Wikipedia View more database links Registry Numbers Types Sources 104615-18-1 CAS Registry Number ChemIDplus 4237267 Reaxys Registry Number Reaxys Citations Types Sources 10440083 PubMed citation Europe PMC 1888997 PubMed citation Europe PMC 1943461 PubMed citation Europe PMC 1953988 PubMed citation Europe PMC 1987452 PubMed citation Europe PMC 24521981 PubMed citation Europe PMC 2883298 PubMed citation Europe PMC 7689104 PubMed citation Europe PMC 7723470 PubMed citation Europe PMC 8007757 PubMed citation Europe PMC 8229772 PubMed citation Europe PMC 8627553 PubMed citation Europe PMC 8760180 PubMed citation Europe PMC 9933143 PubMed citation Europe PMC Last Modified 29 February 2016