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9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one |
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CHEBI:68054 |
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9alpha,11alpha-dihydroxyergosta-4,6,8(14),22-tetraen-3-one |
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An ergostanoid that is ergosta-4,6,8(14),22-tetraene substituted by hydroxy groups at positions 9 and 11 and an oxo group at position 3. Isolated from a myxobacterial strain Sorangiineae, it exhibits activity against colon adinocarcinoma cells. |
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This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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InChI=1S/C28H40O3/c1-17(2)18(3)7-8-19(4)22-11-12-23-24-10-9-20-15-21(29)13-14-27(20,6)28(24,31)25(30)16-26(22,23)5/h7-10,15,17-19,22,25,30-31H,11-14,16H2,1-6H3/b8-7+/t18-,19+,22+,25+,26+,27-,28-/m0/s1 |
GBAGTCNHJJTJIL-YVVZYAQMSA-N |
[H][C@@]1(CCC2=C3C=CC4=CC(=O)CC[C@]4(C)[C@@]3(O)[C@H](O)C[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C |
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Sorangiineae
(NCBI:txid80812)
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Found in
latex
(BTO:0000710).
Previous component: resin; CHCl3-MeOH extract of cell mass and adsorber resin(XAD-16)
of strain
SBNa008
See:
PubMed
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metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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View more via ChEBI Ontology
Outgoing
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9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
(CHEBI:68054)
has role
antineoplastic agent
(CHEBI:35610)
9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
(CHEBI:68054)
has role
metabolite
(CHEBI:25212)
9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
(CHEBI:68054)
is a
11α-hydroxy steroid
(CHEBI:19129)
9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
(CHEBI:68054)
is a
3-oxo-Δ4 steroid
(CHEBI:47909)
9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
(CHEBI:68054)
is a
9-hydroxy steroid
(CHEBI:63644)
9α,11α-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
(CHEBI:68054)
is a
ergostanoid
(CHEBI:50403)
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rel-(11α,22E)-9,11-dihydroxyergosta-4,6,8(14),22-tetraen-3-one
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21559820
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Reaxys Registry Number
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Reaxys
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21513291
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PubMed citation
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Europe PMC
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