CHEBI:132041 - perindoprilat

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ChEBI Name perindoprilat
ChEBI ID CHEBI:132041
Definition A dipeptide obtained by formal condensation of one of the carboxy groups of N-[(1S)-1-carboxyethyl]-L-norvaline with the amino group of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. The major active metabolite of perindopril.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C17H28N2O5
Net Charge 0
Average Mass 340.415
Monoisotopic Mass 340.19982
InChI InChI=1S/C17H28N2O5/c1-3-6-12(16(21)22)18-10(2)15(20)19-13-8-5-4-7-11(13)9-14(19)17(23)24/h10-14,18H,3-9H2,1-2H3,(H,21,22)(H,23,24)/t10-,11-,12-,13-,14-/m0/s1
InChIKey ODAIHABQVKJNIY-PEDHHIEDSA-N
SMILES CCC[C@@H](C(=O)O)N[C@@H](C)C(N1[C@]2(CCCC[C@]2(C[C@H]1C(O)=O)[H])[H])=O
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) See: MetaboLights Study
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
drug metabolite

Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing perindoprilat (CHEBI:132041) has role antihypertensive agent (CHEBI:35674)
perindoprilat (CHEBI:132041) has role drug metabolite (CHEBI:49103)
perindoprilat (CHEBI:132041) has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor (CHEBI:35457)
perindoprilat (CHEBI:132041) is a L-alanine derivative (CHEBI:83943)
perindoprilat (CHEBI:132041) is a dicarboxylic acid (CHEBI:35692)
perindoprilat (CHEBI:132041) is a dipeptide (CHEBI:46761)
perindoprilat (CHEBI:132041) is a organic heterobicyclic compound (CHEBI:27171)
IUPAC Name
N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline
INNs Sources
perindoprilate ChemIDplus
perindoprilato ChemIDplus
perindoprilatum ChemIDplus
perondropilat ChemIDplus
Synonyms Sources
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-carboxybutyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid IUPAC
S 9780 ChemIDplus
S-9780 ChemIDplus
Manual Xrefs Databases
HMDB0060574 HMDB
X94 PDBeChem
View more database links
Registry Numbers Types Sources
4207072 Beilstein Registry Number ChemIDplus
4207072 Reaxys Registry Number Reaxys
95153-31-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
07 December 2016