CHEBI:83326 - tedizolid phosphate

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ChEBI Name tedizolid phosphate
ChEBI ID CHEBI:83326
Definition A phosphate monoester resulting from the formal condensation of equimolar amounts of phosphoric acid with the hydroxy group of tedizolid . It is a prodrug of tedizolid, used for the treatment of acute bacterial skin infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H16FN6O6P
Net Charge 0
Average Mass 450.318
Monoisotopic Mass 450.08530
InChI InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1
InChIKey QCGUSIANLFXSGE-GFCCVEGCSA-N
SMILES C1=C(C=CC(=C1F)C2=CN=C(C=C2)C=3N=NN(N3)C)N4C(O[C@H](C4)COP(O)(=O)O)=O
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
Application(s): prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
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ChEBI Ontology
Outgoing tedizolid phosphate (CHEBI:83326) has role antimicrobial agent (CHEBI:33281)
tedizolid phosphate (CHEBI:83326) has role prodrug (CHEBI:50266)
tedizolid phosphate (CHEBI:83326) has role protein synthesis inhibitor (CHEBI:48001)
tedizolid phosphate (CHEBI:83326) is a carbamate ester (CHEBI:23003)
tedizolid phosphate (CHEBI:83326) is a organofluorine compound (CHEBI:37143)
tedizolid phosphate (CHEBI:83326) is a oxazolidinone (CHEBI:55374)
tedizolid phosphate (CHEBI:83326) is a phosphate monoester (CHEBI:7794)
tedizolid phosphate (CHEBI:83326) is a pyridines (CHEBI:26421)
tedizolid phosphate (CHEBI:83326) is a tetrazoles (CHEBI:35689)
IUPAC Name
[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
Synonyms Sources
Tedizolid phosphate KEGG DRUG
Torezolid phosphate ChemIDplus
TR-701 ChEBI
TR-701 FA ChemIDplus
Brand Name Source
Sivextro ChemIDplus
Manual Xrefs Databases
4873 DrugCentral
D09686 KEGG DRUG
Tedizolid Wikipedia
View more database links
Registry Numbers Types Sources
12031391 Reaxys Registry Number Reaxys
856867-55-5 CAS Registry Number ChemIDplus
856867-55-5 CAS Registry Number KEGG DRUG
Last Modified
22 February 2017