1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine

ChEBI ID	CHEBI:64145

Definition	A tertiary amino compound that consists of cyclohexane having piperidin-1-yl and benzothiophen-2-yl groups attached at position 1. A potent dopamine re-uptake inhibitor with a behavioral profile different from that of phencyclidine (PCP) and similar to that of cocaine.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C19H25NS

Net Charge

Average Mass

299.47400

Monoisotopic Mass

299.17077

InChI

InChI=1S/C19H25NS/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2

InChIKey

RGSVXQJPSWZXOP-UHFFFAOYSA-N

SMILES

C1CCN(CC1)C1(CCCCC1)c1cc2ccccc2s1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.

Application(s):	dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.

ChEBI Ontology
Outgoing	1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145) has role dopamine uptake inhibitor (CHEBI:51039) 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145) is a 1-benzothiophenes (CHEBI:38836) 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145) is a piperidines (CHEBI:26151) 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145) is a tertiary amino compound (CHEBI:50996) 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145) is conjugate base of 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidinium(1+) (CHEBI:64146)

Incoming	1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidinium(1+) (CHEBI:64146) is conjugate acid of 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (CHEBI:64145)

IUPAC Name

1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine

Synonyms	Sources
1-(1-Benzo(b)thien-2-ylcyclohexyl)piperidine	ChemIDplus
1-(1-benzo[b]thien-2-ylcyclohexyl)piperidine	ChEBI
1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine	ChEBI
1-Btcp	ChemIDplus
benocyclidine	ChEBI
BTCP	ChemIDplus
GK 13	ChemIDplus
GK-13	ChemIDplus
N-(1-(2-Benzo(b)thiophenyl)cyclohexyl)piperidine	ChemIDplus
N-[1-(2-benzo[b]thiophenyl)cyclohexyl]piperidine	ChEBI

Last Modified

21 September 2021