CHEBI:102248 - EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor

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ChEBI Name EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
ChEBI ID CHEBI:102248
Definition An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).
Stars This entity has been manually annotated by the ChEBI Team.
ChEBI Ontology
Outgoing EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248) is a EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor (CHEBI:76902)
Incoming daprodustat (CHEBI:229223) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248)
dimethyloxalylglycine (CHEBI:102218) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248)
roxadustat (CHEBI:132774) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248)
Synonyms Sources
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors ChEBI
EC 1.14.11.29 inhibitor ChEBI
EC 1.14.11.29 inhibitors ChEBI
HIF hydroxylase inhibitor ChEBI
HIF hydroxylase inhibitors ChEBI
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor ChEBI
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors ChEBI
prolyl 4-hydroxylase inhibitor ChEBI
prolyl 4-hydroxylase inhibitors ChEBI
Last Modified
16 January 2024