CHEBI:7819 - oxamniquine

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ChEBI Name oxamniquine ChEBI ID CHEBI:7819 Definition A racemate comprising equimolar amounts of (R)- and (S)-oxamniquine. An anthelmintic, it is administered orally for the treatment of schistomiasis caused by Schistosoma mansoni (but not by other Schistosoma species); intramuscular administration is no longer used as it causes severe pain at the injection site. Stars This entity has been manually annotated by the ChEBI Team. Wikipedia License Read full article at Wikipedia Formula C14H21N3O3 Net Charge 0 Average Mass 279.33480 Monoisotopic Mass 279.15829 Roles Classification Application(s): schistosomicide drug Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma. View more via ChEBI Ontology ChEBI Ontology Outgoing oxamniquine (CHEBI:7819) has part (R)-oxamniquine (CHEBI:78417) oxamniquine (CHEBI:7819) has part (S)-oxamniquine (CHEBI:78418) oxamniquine (CHEBI:7819) has role schistosomicide drug (CHEBI:38941) oxamniquine (CHEBI:7819) is a racemate (CHEBI:60911) IUPAC Name rac-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol INNs Sources oxamniquina WHO MedNet oxamniquine WHO MedNet oxamniquine WHO MedNet oxamniquinum WHO MedNet Synonyms Sources (±)-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol ChemIDplus (±)-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline ChemIDplus (±)-{2-[(isopropylamino)methyl]-7-nitro-1,2,3,4-tetrahydroquinolin-6-yl}methanol ChemIDplus 1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol ChemIDplus 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline ChemIDplus rac-1,2,3,4-tetrahydro-2-{[(1-methylethyl)amino]methyl}-7-nitro-6-quinolinemethanol ChemIDplus rac-6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline ChemIDplus rac-oxamniquine ChEBI UK 4271 ChemIDplus UK-4271 ChemIDplus UK4271 ChEBI Brand Names Sources Mansil KEGG DRUG Vansil KEGG DRUG Manual Xrefs Databases C07341 KEGG COMPOUND D00460 KEGG DRUG DB01096 DrugBank HMDB0015228 HMDB OAQ PDBeChem Oxamniquine Wikipedia US3821228 Patent View more database links Registry Numbers Types Sources 21738-42-1 CAS Registry Number KEGG COMPOUND 21738-42-1 CAS Registry Number ChemIDplus 485597 Reaxys Registry Number Reaxys Citations Types Sources 10321028 PubMed citation Europe PMC 11516919 PubMed citation Europe PMC 1198006 PubMed citation Europe PMC 17988075 PubMed citation Europe PMC 2083150 PubMed citation Europe PMC 21500322 PubMed citation Europe PMC 23450530 PubMed citation Europe PMC 2490562 PubMed citation Europe PMC 2638729 PubMed citation Europe PMC 3082231 PubMed citation Europe PMC 3127959 PubMed citation Europe PMC 349665 PubMed citation Europe PMC 4203813 PubMed citation Europe PMC 4205106 PubMed citation Europe PMC 4977703 PubMed citation Europe PMC 734715 PubMed citation Europe PMC 7767464 PubMed citation Europe PMC 823880 PubMed citation Europe PMC 8839672 PubMed citation Europe PMC Last Modified 21 April 2017