CHEBI:131513 - tranylcypromine hydrochloride

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ChEBI Name tranylcypromine hydrochloride
ChEBI ID CHEBI:131513
Definition A racemate comprising equal amounts of (1R,2S)- and (1S,2R)-tranylcypromine hydrochloride. An irreversible monoamine oxidase inhibitor that is used as an antidepressant.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Biological Role(s): EC 1.4.3.4 (monoamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor
An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of lysine-specific histone demethylase 1A (EC 1.14.99.66).
Application(s): antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tranylcypromine hydrochloride (CHEBI:131513) has part (1R,2S)-tranylcypromine hydrochloride (CHEBI:131514)
tranylcypromine hydrochloride (CHEBI:131513) has part (1S,2R)-tranylcypromine hydrochloride (CHEBI:131516)
tranylcypromine hydrochloride (CHEBI:131513) has role antidepressant (CHEBI:35469)
tranylcypromine hydrochloride (CHEBI:131513) has role anxiolytic drug (CHEBI:35474)
tranylcypromine hydrochloride (CHEBI:131513) has role EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor (CHEBI:131509)
tranylcypromine hydrochloride (CHEBI:131513) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623)
tranylcypromine hydrochloride (CHEBI:131513) is a racemate (CHEBI:60911)
IUPAC Names
rac-(1R,2S)-2-phenylcyclopropan-1-amine hydrochloride
rac-(1R,2S)-2-phenylcyclopropan-1-aminium chloride
Synonyms Sources
(±)-trans-2-phenylcyclopropylamine hydrochloride ChEBI
(1R*,2S*)-2-phenylcyclopropan-1-amine hydrochloride ChEBI
DL-tranylcypromine hydrochloride ChEBI
rac-tranylcypromine hydrochloride ChEBI
trans-2-phenylcyclopropylamine hydrochloride ChEBI
Registry Number Type Source
8220297 Reaxys Registry Number Reaxys
Last Modified
11 March 2016