CHEBI:92842 - dilazep

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ChEBI Name dilazep
ChEBI ID CHEBI:92842
Definition A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C31H44N2O10
Net Charge 0
Average Mass 604.697
Monoisotopic Mass 604.29960
InChI InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3
InChIKey QVZCXCJXTMIDME-UHFFFAOYSA-N
SMILES COC1=CC(=CC(OC)=C1OC)C(=O)OCCCN1CCCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1
Roles Classification
Application(s): vasodilator agent
A drug used to cause dilation of the blood vessels.
platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
cardioprotective agent
Any protective agent that is able to prevent damage to the heart.
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ChEBI Ontology
Outgoing dilazep (CHEBI:92842) has role cardioprotective agent (CHEBI:77307)
dilazep (CHEBI:92842) has role platelet aggregation inhibitor (CHEBI:50427)
dilazep (CHEBI:92842) has role vasodilator agent (CHEBI:35620)
dilazep (CHEBI:92842) is a benzoate ester (CHEBI:36054)
dilazep (CHEBI:92842) is a diazepane (CHEBI:38823)
dilazep (CHEBI:92842) is a diester (CHEBI:51307)
dilazep (CHEBI:92842) is a methoxybenzenes (CHEBI:51683)
dilazep (CHEBI:92842) is conjugate base of dilazep(2+) (CHEBI:170000)
Incoming dilazep(2+) (CHEBI:170000) is conjugate acid of dilazep (CHEBI:92842)
IUPAC Name
1,4-diazepane-1,4-diyldipropane-3,1-diyl bis(3,4,5-trimethoxybenzoate)
INNs Sources
dilazep WHO MedNet
dilazep WHO MedNet
dilazep WHO MedNet
dilazepum WHO MedNet
Synonyms Sources
N,N'-bis[3-(3,4,5-trimethoxybenzoyloxy)propyl]homopiperazine ChEBI
tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanediyl-3,4,5-trimethoxybenzoate ChEBI
Manual Xrefs Databases
2965 ChemSpider
893 DrugCentral
8DZ PDBeChem
D07843 KEGG DRUG
DB13715 DrugBank
Dilazep Wikipedia
LSM-3068 LINCS
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Registry Number Type Source
35898-87-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 April 2021