CHEBI:9688 - trichodermin

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ChEBI Name trichodermin
ChEBI ID CHEBI:9688
Definition A tetracyclic spiroepoxide which acts as an antifungal and protein synthesis inhibitor.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:552470
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Formula C17H24O4
Net Charge 0
Average Mass 292.37010
Monoisotopic Mass 292.167
InChI InChI=1S/C17H24O4/c1-10-5-6-15(3)12(7-10)21-14-8-13(20-11(2)18)16(15,4)17(14)9-19-17/h7,12-14H,5-6,8-9H2,1-4H3/t12-,13-,14-,15+,16-,17-/m1/s1
InChIKey HNEGCRMUYSKRRR-NWHWRWDZSA-N
SMILES [H][C@]12C[C@@H](OC(C)=O)[C@](C)([C@@]3(C)CCC(C)=C[C@@]3([H])O1)[C@@]21CO1
Roles Classification
Biological Role(s): antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing trichodermin (CHEBI:9688) has role antifungal agent (CHEBI:35718)
trichodermin (CHEBI:9688) has role antineoplastic agent (CHEBI:35610)
trichodermin (CHEBI:9688) has role protein synthesis inhibitor (CHEBI:48001)
trichodermin (CHEBI:9688) is a epoxide (CHEBI:32955)
trichodermin (CHEBI:9688) is a organic heterotetracyclic compound (CHEBI:38163)
IUPAC Name
(4β,12R)-12,13-epoxytrichothec-9-en-4-yl acetate
Synonym Source
12,13-Epoxytrichothec-9-en-4-ol acetate ChemIDplus
Database Links Databases
C00003195 KNApSAcK
C09741 KEGG COMPOUND
NL302527 Patent
View more database links
Registry Numbers Types Sources
4682-50-2 CAS Registry Number KEGG COMPOUND
4682-50-2 CAS Registry Number ChemIDplus
6868411 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
4750433 PubMed citation Europe PMC
6757231 PubMed citation Europe PMC
Last Modified
28 July 2014