CHEBI:74723 - 3,6-diaminoacridine dihydrochloride

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ChEBI Name 3,6-diaminoacridine dihydrochloride
ChEBI ID CHEBI:74723
Definition A hydrochloride resulting from the reaction of 3,6-diaminoacridine with 2 mol eq. of hydrogen chloride.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C13H13Cl2N3
Net Charge 0
Average Mass 282.16800
Monoisotopic Mass 281.04865
InChI InChI=1S/C13H11N3.2ClH/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;;/h1-7H,14-15H2;2*1H
InChIKey YHIHFKAEJAVELI-UHFFFAOYSA-N
SMILES Cl.Cl.Nc1ccc2cc3ccc(N)cc3nc2c1
Roles Classification
Biological Role(s): antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
intercalator
A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
Application(s): antiseptic drug
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
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ChEBI Ontology
Outgoing 3,6-diaminoacridine dihydrochloride (CHEBI:74723) has part 3,6-diaminoacridine(2+) (CHEBI:74713)
3,6-diaminoacridine dihydrochloride (CHEBI:74723) has role antibacterial agent (CHEBI:33282)
3,6-diaminoacridine dihydrochloride (CHEBI:74723) has role antiseptic drug (CHEBI:48218)
3,6-diaminoacridine dihydrochloride (CHEBI:74723) has role carcinogenic agent (CHEBI:50903)
3,6-diaminoacridine dihydrochloride (CHEBI:74723) has role intercalator (CHEBI:24853)
3,6-diaminoacridine dihydrochloride (CHEBI:74723) is a hydrochloride (CHEBI:36807)
Incoming acriflavinium chloride (CHEBI:74728) has part 3,6-diaminoacridine dihydrochloride (CHEBI:74723)
IUPAC Name
acridine-3,6-diamine dihydrochloride
Synonyms Sources
3,6-diaminoacridinium chloride hydrochloride ChemIDplus
3-amino-6-ammonioacridinium dichloride IUPAC
proflavin.2HCl ChEBI
proflavine dihydrochloride ChemIDplus
Registry Number Type Source
531-73-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
4639267 PubMed citation Europe PMC
7009393 PubMed citation Europe PMC
Last Modified
31 July 2013