CHEBI:149534 - polyhexamethylene biguanide hydrochloride

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ChEBI Name polyhexamethylene biguanide hydrochloride
ChEBI ID CHEBI:149534
Definition A hydrochloride salt of polyhexamethylene biguanide. It is a broad spectrum and fast acting bactericide which is used for the formulation of disinfectants and sanitisers.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula (ClH)x.(C8H17N5)n
Net Charge 0
Roles Classification
Biological Role(s): disinfectant
An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
Application(s): dermatologic drug
A drug used to treat or prevent skin disorders or for the routine care of skin.
ophthalmology drug
Any compound used for the treatment of eye conditions or eye diseases.
antiseptic drug
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
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ChEBI Ontology
Outgoing polyhexamethylene biguanide hydrochloride (CHEBI:149534) has part polyhexamethylene biguanide(2+) (CHEBI:149538)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role antibacterial agent (CHEBI:33282)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role antifungal agent (CHEBI:35718)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role antiseptic drug (CHEBI:48218)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role dermatologic drug (CHEBI:50177)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role disinfectant (CHEBI:48219)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) has role ophthalmology drug (CHEBI:66981)
polyhexamethylene biguanide hydrochloride (CHEBI:149534) is a hydrochloride (CHEBI:36807)
Synonyms Sources
hexamethylenediamine polymer hydrochloride ChEBI
PHMB hydrochloride ChEBI
PHMB-HCl ChEBI
polihexanide HCl DrugBank
polihexanide hydrochloride DrugBank
poly(hexamethylenebiguanide) hydrochloride ChEBI
poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) hydrochloride ChemIDplus
Brand Names Sources
Cosmocil ChemIDplus
Cosmoquil CQ ChemIDplus
poly(hexamethylene) biguanide hydrochloride ChemIDplus
Prontoderm ChemIDplus
Prontosan ChemIDplus
Reputex 20 ChemIDplus
TriGene ChemIDplus
Vantocil 1B ChemIDplus
Vantocil TG ChemIDplus
Vantosan ChemIDplus
Manual Xrefs Databases
D08399 KEGG DRUG
DBSALT002168 DrugBank
View more database links
Registry Number Type Source
32289-58-0 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
14640452 PubMed citation Europe PMC
17346020 PubMed citation Europe PMC
18332553 PubMed citation Europe PMC
19914741 PubMed citation Europe PMC
21356204 PubMed citation Europe PMC
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23313712 PubMed citation Europe PMC
26456666 PubMed citation Europe PMC
28497633 PubMed citation Europe PMC
28814284 PubMed citation Europe PMC
29029044 PubMed citation Europe PMC
30384305 PubMed citation Europe PMC
31936456 PubMed citation Europe PMC
Last Modified
22 April 2020