CHEBI:145698 - amezinium

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ChEBI Name amezinium
ChEBI ID CHEBI:145698
Definition A pyridazinium ion that is pyridazin-1-ium which is substituted by a phenyl, amino and methoxy groups at positions 1, 4 and 6, respectively.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C11H12N3O
Net Charge +1
Average Mass 202.236
Monoisotopic Mass 202.09749
InChI InChI=1S/C11H11N3O/c1-15-11-7-9(12)8-13-14(11)10-5-3-2-4-6-10/h2-8,12H,1H3/p+1
InChIKey VXROHTDSRBRJLN-UHFFFAOYSA-O
SMILES O(C=1[N+](=NC=C(C1)N)C2=CC=CC=C2)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 1.4.3.4 (monoamine oxidase) inhibitor
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Application(s): antihypotensive agent
A cardiovascular drug that tends to raise reduced blood pressure.
sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
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ChEBI Ontology
Outgoing amezinium (CHEBI:145698) has role adrenergic uptake inhibitor (CHEBI:35640)
amezinium (CHEBI:145698) has role antihypotensive agent (CHEBI:137431)
amezinium (CHEBI:145698) has role EC 1.4.3.4 (monoamine oxidase) inhibitor (CHEBI:38623)
amezinium (CHEBI:145698) has role sympathomimetic agent (CHEBI:35524)
amezinium (CHEBI:145698) is a aromatic ether (CHEBI:35618)
amezinium (CHEBI:145698) is a primary arylamine (CHEBI:50471)
amezinium (CHEBI:145698) is a pyridazinium ion (CHEBI:145699)
Incoming amezinium metilsulfate (CHEBI:31201) has part amezinium (CHEBI:145698)
IUPAC Name
4-amino-6-methoxy-1-phenylpyridazin-1-ium
Synonyms Sources
4-amino-6-methoxy-1-phenyl-pyridazinium ChemIDplus
amezinium(1+) ChEBI
Manual Xref Database
153 DrugCentral
View more database links
Registry Numbers Types Sources
4141517 Beilstein Registry Number Beilstein
41658-78-0 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
17 December 2019