CHEBI:65672 - cratoxyarborenone B

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ChEBI Name cratoxyarborenone B
ChEBI ID CHEBI:65672
Definition A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 5 and 7 and two isoprenyl groups at positions 2 and 8 respectively. It is isolated from Cratoxylum Sumatranum and exhibits cytotoxicity towards the KB (human oral epidermoid) cancer cell line.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C23H24O6
Net Charge 0
Average Mass 396.43310
Monoisotopic Mass 396.15729
InChI InChI=1S/C23H24O6/c1-11(2)5-7-13-15(24)9-17(26)23-19(13)22(28)20-18(29-23)10-16(25)14(21(20)27)8-6-12(3)4/h5-6,9-10,24-27H,7-8H2,1-4H3
InChIKey AVGUAOZYPIBDIZ-UHFFFAOYSA-N
SMILES CC(C)=CCc1c(O)cc2oc3c(O)cc(O)c(CC=C(C)C)c3c(=O)c2c1O
Metabolite of Species Details
Cratoxylum Sumatranum (IPNI:433074-1) Found in leaf (BTO:0000713). See: PubMed
Cratoxylum Sumatranum (IPNI:433074-1) Found in twig (BTO:0001411). See: PubMed
Cratoxylum Sumatranum (IPNI:433074-1) Found in stem (BTO:0001300). Previous component: stem bark; See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cratoxyarborenone B (CHEBI:65672) has role antineoplastic agent (CHEBI:35610)
cratoxyarborenone B (CHEBI:65672) has role metabolite (CHEBI:25212)
cratoxyarborenone B (CHEBI:65672) is a polyphenol (CHEBI:26195)
cratoxyarborenone B (CHEBI:65672) is a xanthones (CHEBI:51149)
IUPAC Name
1,3,5,7-tetrahydroxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
Synonym Source
1,3,5,7-tetrahydroxy-2,8-diisoprenylxanthone ChEBI
Registry Number Type Source
9094709 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
11908969 PubMed citation Europe PMC
Last Modified
18 December 2012