lomefloxacin hydrochloride (CHEBI:6518)

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ChEBI Name	lomefloxacin hydrochloride

ChEBI ID	CHEBI:6518

Definition	The hydrochloride salt of lomefloxacin. It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C17H20ClF2N3O3

Net Charge

Average Mass

387.80900

Monoisotopic Mass

387.11613

InChI

InChI=1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H

InChIKey

KXEBLAPZMOQCKO-UHFFFAOYSA-N

SMILES

Cl.CCn1cc(C(O)=O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12

Roles Classification
Biological Role(s):	antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.

Application(s):	photosensitizing agent A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.

ChEBI Ontology
Outgoing	lomefloxacin hydrochloride (CHEBI:6518) has part lomefloxacin (CHEBI:116278) lomefloxacin hydrochloride (CHEBI:6518) has role antimicrobial agent (CHEBI:33281) lomefloxacin hydrochloride (CHEBI:6518) has role antitubercular agent (CHEBI:33231) lomefloxacin hydrochloride (CHEBI:6518) has role photosensitizing agent (CHEBI:47868) lomefloxacin hydrochloride (CHEBI:6518) is a hydrochloride (CHEBI:36807)

IUPAC Name

1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

Synonyms	Sources
(±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochloride	ChemIDplus
lomefloxacin HCl	ChemIDplus

Last Modified

16 November 2010