CHEBI:4464 - dexchlorpheniramine

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ChEBI Name dexchlorpheniramine
ChEBI ID CHEBI:4464
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H19ClN2
Net Charge 0
Average Mass 274.78800
Monoisotopic Mass 274.12368
InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1
InChIKey SOYKEARSMXGVTM-HNNXBMFYSA-N
SMILES CN(C)CC[C@@H](c1ccc(Cl)cc1)c1ccccn1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
(via chlorphenamine )
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
(via chlorphenamine )
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
(via chlorphenamine )
Application(s): serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
(via chlorphenamine )
antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
(via chlorphenamine )
H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
(via chlorphenamine )
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
(via chlorphenamine )
antipruritic drug
A drug, usually applied topically, that relieves pruritus (itching).
(via chlorphenamine )
anti-allergic agent
A drug used to treat allergic reactions.
(via chlorphenamine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dexchlorpheniramine (CHEBI:4464) is a chlorphenamine (CHEBI:52010)
dexchlorpheniramine (CHEBI:4464) is enantiomer of levochlorpheniramine (CHEBI:52013)
Incoming levochlorpheniramine (CHEBI:52013) is enantiomer of dexchlorpheniramine (CHEBI:4464)
IUPAC Name
(3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
INNs Sources
dexchlorpheniramine KEGG DRUG
dexchlorpheniraminum ChemIDplus
dexclorfeniramina ChemIDplus
Synonyms Sources
(+)-chlorpheniramine NIST Chemistry WebBook
(S)-(+)-2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine NIST Chemistry WebBook
(S)-γ-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine NIST Chemistry WebBook
d-chlorpheniramine ChemIDplus
Dexchlorpheniramine KEGG COMPOUND
Brand Name Source
Dapriton KEGG DRUG
Manual Xrefs Databases
4411 DrugCentral
C06946 KEGG COMPOUND
D07803 KEGG DRUG
Dexchlorpheniramine Wikipedia
LSM-5517 LINCS
US3061517 Patent
View more database links
Registry Numbers Types Sources
25523-97-1 CAS Registry Number ChemIDplus
25523-97-1 CAS Registry Number NIST Chemistry WebBook
6483076 Beilstein Registry Number Beilstein
87360 Beilstein Registry Number Beilstein
Last Modified
22 February 2017