CHEBI:520819 - flufenamate

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ChEBI Name flufenamate
ChEBI ID CHEBI:520819
Definition A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of flufenamic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C14H9F3NO2
Net Charge -1
Average Mass 280.22200
Monoisotopic Mass 280.05909
InChI InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)/p-1
InChIKey LPEPZBJOKDYZAD-UHFFFAOYSA-M
SMILES [O-]C(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing flufenamate (CHEBI:520819) has functional parent (trifluoromethyl)benzene (CHEBI:36810)
flufenamate (CHEBI:520819) has functional parent anthranilic acid (CHEBI:30754)
flufenamate (CHEBI:520819) has functional parent diphenylamine (CHEBI:4640)
flufenamate (CHEBI:520819) has role antipyretic (CHEBI:35493)
flufenamate (CHEBI:520819) has role non-narcotic analgesic (CHEBI:35481)
flufenamate (CHEBI:520819) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
flufenamate (CHEBI:520819) is a aromatic amino-acid anion (CHEBI:63473)
flufenamate (CHEBI:520819) is a monocarboxylic acid anion (CHEBI:35757)
flufenamate (CHEBI:520819) is conjugate base of flufenamic acid (CHEBI:42638)
Incoming flufenamic acid (CHEBI:42638) is conjugate acid of flufenamate (CHEBI:520819)
IUPAC Name
2-{[3-(trifluoromethyl)phenyl]amino}benzoate
Synonym Source
2-(3-(trifluoromethyl)phenylamino)benzoate ChEBI
Registry Number Type Source
5981335 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
4012673 PubMed citation Europe PMC
7093245 PubMed citation Europe PMC
Last Modified
31 January 2012