CHEBI:9381 - T-2 toxin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name T-2 toxin
ChEBI ID CHEBI:9381
Definition A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C24H34O9
Net Charge 0
Average Mass 466.527
Monoisotopic Mass 466.22028
InChI InChI=1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
InChIKey BXFOFFBJRFZBQZ-QYWOHJEZSA-N
SMILES [H][C@@]12O[C@]3([H])C=C(C)[C@H](C[C@]3(COC(C)=O)[C@@](C)([C@H](OC(C)=O)[C@H]1O)[C@]21CO1)OC(=O)CC(C)C
Metabolite of Species Details
Fusarium sp.rotrichioides (NCBI:txid5514) of strain NRRL3299 See: PubMed
Fusarium graminearum (NCBI:txid5518) of strain Z-3639 See: PubMed
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): DNA synthesis inhibitor
Any substance that inhibits the synthesis of DNA.
fungal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
mycotoxin
Poisonous substance produced by fungi.
(via trichothecene )
cardiotoxic agent
A role played by a chemical compound exihibiting itself through the ability to induce damage to the heart and cardiomyocytes.
neurotoxin
A poison that interferes with the functions of the nervous system.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing T-2 toxin (CHEBI:9381) has functional parent HT-2 toxin (CHEBI:138861)
T-2 toxin (CHEBI:9381) has role apoptosis inducer (CHEBI:68495)
T-2 toxin (CHEBI:9381) has role cardiotoxic agent (CHEBI:50912)
T-2 toxin (CHEBI:9381) has role DNA synthesis inhibitor (CHEBI:59517)
T-2 toxin (CHEBI:9381) has role environmental contaminant (CHEBI:78298)
T-2 toxin (CHEBI:9381) has role fungal metabolite (CHEBI:76946)
T-2 toxin (CHEBI:9381) has role mycotoxin (CHEBI:25442)
T-2 toxin (CHEBI:9381) has role neurotoxin (CHEBI:50910)
T-2 toxin (CHEBI:9381) is a acetate ester (CHEBI:47622)
T-2 toxin (CHEBI:9381) is a organic heterotetracyclic compound (CHEBI:38163)
T-2 toxin (CHEBI:9381) is a trichothecene (CHEBI:55517)
IUPAC Name
4β,15-bis(acetyloxy)-3α-hydroxy-12,13-epoxytrichothec-9-en-8α-yl 3-methylbutanoate
Synonyms Sources
(3α,4β,8α)-12,13-epoxy-4,15-diacetate 8-(3-methylbutanoate)trichothec-9-ene-3,4,8,15-tetrol ChEBI
3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-δ-9-trichothecene ChemIDplus
4β,15-diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene ChEBI
fusariotoxin T 2 ChemIDplus
fusariotoxin T-2 ChEBI
fusariotoxine T2 ChemIDplus
insariotoxin ChemIDplus
isaritoxin ChemIDplus
mycotoxin T-2 ChemIDplus
T-2 mycotoxin ChemIDplus
T2 toxin ChemIDplus
T2-trichothecene ChemIDplus
toxin T2 ChemIDplus
Manual Xrefs Databases
4447526 ChemSpider
C00003192 KNApSAcK
C09738 KEGG COMPOUND
CPD-18416 MetaCyc
FDB015515 FooDB
HMDB0036600 HMDB
T-2_mycotoxin Wikipedia
View more database links
Registry Numbers Types Sources
21259-20-1 CAS Registry Number ChemIDplus
21259-20-1 CAS Registry Number NIST Chemistry WebBook
3575695 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
16604118 PubMed citation Europe PMC
22069741 PubMed citation Europe PMC
28430618 PubMed citation Europe PMC
29433086 PubMed citation Europe PMC
31570981 PubMed citation Europe PMC
31653066 PubMed citation Europe PMC
31886226 PubMed citation Europe PMC
31895560 PubMed citation Europe PMC
31981685 PubMed citation Europe PMC
32214355 PubMed citation Europe PMC
32229328 PubMed citation Europe PMC
32451776 PubMed citation Europe PMC
32545742 PubMed citation Europe PMC
32656676 PubMed citation Europe PMC
32698025 PubMed citation Europe PMC
32698434 PubMed citation Europe PMC
32708466 PubMed citation Europe PMC
32751656 PubMed citation Europe PMC
32777337 PubMed citation Europe PMC
32777540 PubMed citation Europe PMC
32795851 PubMed citation Europe PMC
32798696 PubMed citation Europe PMC
32803179 PubMed citation Europe PMC
32805342 PubMed citation Europe PMC
32839860 PubMed citation Europe PMC
32842569 PubMed citation Europe PMC
32910237 PubMed citation Europe PMC
32928346 PubMed citation Europe PMC
32990831 PubMed citation Europe PMC
IND606948730 Agricola citation Europe PMC
Last Modified
23 November 2020