CHEBI:82467 - Evans blue

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ChEBI Name Evans blue
ChEBI ID CHEBI:82467
Definition An organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:87630
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Formula C34H24N6Na4O14S4
Net Charge 0
Average Mass 960.80500
Monoisotopic Mass 959.98241
InChI InChI=1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4
InChIKey ATNOAWAQFYGAOY-UHFFFAOYSA-J
SMILES [Na+].[Na+].[Na+].[Na+].Cc1cc(ccc1N=Nc1ccc2c(cc(c(N)c2c1O)S([O-])(=O)=O)S([O-])(=O)=O)-c1ccc(N=Nc2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c1
Roles Classification
Biological Role(s): teratogenic agent
A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
sodium channel blocker
An agent that inhibits sodium influx through cell membranes.
Application(s): histological dye
A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
fluorochrome
A fluorescent dye used to stain biological specimens.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing Evans blue (CHEBI:82467) has part Evans blue(4−) (CHEBI:87636)
Evans blue (CHEBI:82467) has role fluorochrome (CHEBI:51217)
Evans blue (CHEBI:82467) has role histological dye (CHEBI:77178)
Evans blue (CHEBI:82467) has role sodium channel blocker (CHEBI:38633)
Evans blue (CHEBI:82467) has role teratogenic agent (CHEBI:50905)
Evans blue (CHEBI:82467) is a organic sodium salt (CHEBI:38700)
IUPAC Name
tetrasodium 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)
Synonyms Sources
4,4'-Bis(1-amino-8-hydroxy-2,4-disulfo-7-naphthylazo)-3,3'-bitolyl, tetrasodium salt ChemIDplus
4,4'-Bis(1-amino-8-hydroxy-2,4-disulpho-7-naphthylazo)-3,3'-bitolyl, tetrasodium salt ChemIDplus
4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulfo)naphthylazo)-3,3'-bitolyl, tetrasodium salt ChemIDplus
4,4'-Bis(7-(1-amino-8-hydroxy-2,4-disulpho)naphthylazo)-3,3'-bitolyl, tetrasodium salt ChemIDplus
azovan blue ChEBI
C.I. 23860 ChEBI
C.I. Direct Blue 53 ChemIDplus
C.I. direct blue 53 tetrasodium salt ChemIDplus
direct blue 53 ChEBI
Manual Xrefs Databases
C19422 KEGG COMPOUND
Evans_Blue_(dye) Wikipedia
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Registry Numbers Types Sources
314-13-6 CAS Registry Number ChemIDplus
7110511 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017