CHEBI:65311 - corticotropin-releasing hormone

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ChEBI Name corticotropin-releasing hormone
ChEBI ID CHEBI:65311
Definition A family of peptide hormones derived from a 191-membered prehormone, secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. The first full sequence was discovered in sheep, those in rats and humans differ from the ovine sequence by 7 amino acids.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): neurotransmitter
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via peptide hormone )
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ChEBI Ontology
Outgoing corticotropin-releasing hormone (CHEBI:65311) has role neurotransmitter (CHEBI:25512)
corticotropin-releasing hormone (CHEBI:65311) is a biomacromolecule (CHEBI:33694)
corticotropin-releasing hormone (CHEBI:65311) is a peptide hormone (CHEBI:25905)
corticotropin-releasing hormone (CHEBI:65311) is a polypeptide (CHEBI:15841)
Incoming corticotropin-releasing hormone (human) (CHEBI:65312) is a corticotropin-releasing hormone (CHEBI:65311)
corticotropin-releasing hormone (ovine) (CHEBI:65307) is a corticotropin-releasing hormone (CHEBI:65311)
Synonyms Sources
corticotropin-releasing factor ChEBI
CRH ChEBI
Manual Xref Database
Corticotropin-releasing_hormone Wikipedia
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Citations Waiting for Citations Types Sources
22494987 PubMed citation Europe PMC
6267699 PubMed citation Europe PMC
Last Modified
24 July 2012