CHEBI:61022 - naproxol

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ChEBI Name naproxol
ChEBI ID CHEBI:61022
Definition An aromatic ether in which the substituents on oxygen are 6-[(2S)-1-hydroxypropan-2-yl]-2-naphthyl and methyl.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C14H16O2
Net Charge 0
Average Mass 216.27560
Monoisotopic Mass 216.11503
InChI InChI=1S/C14H16O2/c1-10(9-15)11-3-4-13-8-14(16-2)6-5-12(13)7-11/h3-8,10,15H,9H2,1-2H3/t10-/m1/s1
InChIKey LTRANDSQVZFZDG-SNVBAGLBSA-N
SMILES COc1ccc2cc(ccc2c1)[C@H](C)CO
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing naproxol (CHEBI:61022) has role antipyretic (CHEBI:35493)
naproxol (CHEBI:61022) has role non-narcotic analgesic (CHEBI:35481)
naproxol (CHEBI:61022) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
naproxol (CHEBI:61022) is a aromatic ether (CHEBI:35618)
IUPAC Name
(2S)-2-(6-methoxy-2-naphthyl)propan-1-ol
INN Source
naproxol KEGG DRUG
Synonyms Sources
(−)-(S)-6-methoxy-β-methyl-2-naphthaleneethanol ChemIDplus
(−)-2-(6-methoxy-2-naphthyl)-1-propanol ChemIDplus
(−)-6-methoxy-β-methyl-2-naphthaleneethanol ChemIDplus
(S)-(−)-2-(6-methoxy-2-naphthyl)-1-propanol ChemIDplus
Manual Xrefs Databases
D05121 KEGG DRUG
LSM-2742 LINCS
View more database links
Registry Numbers Types Sources
26159-36-4 CAS Registry Number ChemIDplus
7702132 Reaxys Registry Number Reaxys
Last Modified
25 February 2016