acyclovir (CHEBI:2453)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	acyclovir

ChEBI ID	CHEBI:2453

Definition	An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:40459

Supplier Information

Download	Molfile XML SDF

more structures >>

Wikipedia	License

Read full article at Wikipedia

Formula

C8H11N5O3

Net Charge

Average Mass

225.20460

Monoisotopic Mass

225.08619

InChI

InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

InChIKey

MKUXAQIIEYXACX-UHFFFAOYSA-N

SMILES

Nc1nc2n(COCCO)cnc2c(=O)[nH]1

Roles Classification
Biological Role(s):	antiviral drug A substance used in the prophylaxis or therapy of virus diseases. antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.

Application(s):	antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

ChEBI Ontology
Outgoing	acyclovir (CHEBI:2453) has functional parent guanine (CHEBI:16235) acyclovir (CHEBI:2453) has role antimetabolite (CHEBI:35221) acyclovir (CHEBI:2453) has role antiviral drug (CHEBI:36044) acyclovir (CHEBI:2453) is a 2-aminopurines (CHEBI:20702) acyclovir (CHEBI:2453) is a oxopurine (CHEBI:25810)

IUPAC Name

2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one

Synonym	Source
acycloguanosine	ChEBI

Brand Name	Source
Zovir	DrugBank

Last Modified

13 June 2017