CHEBI:135745 - prednisolone succinate

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name prednisolone succinate ChEBI ID CHEBI:135745 Definition A hemisuccinate resulting from the formal condensation of the 21-hydroxy group prednisolone with one of the carboxy groups of succinic acid. It is used to treat mild to moderate non-infectious eye allergies and inflammation, including damage caused by chemical and thermal burns. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C25H32O8 Net Charge 0 Average Mass 460.523 Monoisotopic Mass 460.20972 InChI InChI=1S/C25H32O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h7,9,11,16-18,22,27,32H,3-6,8,10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1 InChIKey APGDTXUMTIZLCJ-CGVGKPPMSA-N SMILES [H][C@@]12CC[C@](O)(C(=O)COC(=O)CCC(O)=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C Roles Classification Chemical Role(s): Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid ) Application(s): anti-inflammatory drug A substance that reduces or suppresses inflammation. View more via ChEBI Ontology ChEBI Ontology Outgoing prednisolone succinate (CHEBI:135745) has functional parent prednisolone (CHEBI:8378) prednisolone succinate (CHEBI:135745) has functional parent succinic acid (CHEBI:15741) prednisolone succinate (CHEBI:135745) has role anti-inflammatory drug (CHEBI:35472) prednisolone succinate (CHEBI:135745) is a 11β-hydroxy steroid (CHEBI:35346) prednisolone succinate (CHEBI:135745) is a 17α-hydroxy steroid (CHEBI:35342) prednisolone succinate (CHEBI:135745) is a 20-oxo steroid (CHEBI:36885) prednisolone succinate (CHEBI:135745) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166) prednisolone succinate (CHEBI:135745) is a hemisuccinate (CHEBI:138979) prednisolone succinate (CHEBI:135745) is a tertiary α-hydroxy ketone (CHEBI:139592) prednisolone succinate (CHEBI:135745) is conjugate acid of prednisolone succinate(1−) (CHEBI:157677) Incoming prednisolone succinate(1−) (CHEBI:157677) is conjugate base of prednisolone succinate (CHEBI:135745) IUPAC Name 4-[(11β,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl)oxy]-4-oxobutanoic acid Synonyms Sources 11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate ChEBI Δ1-hydrocortisone 21-hemisuccinate ChEBI Δ1-hydrocortisone succinate ChEBI prednisolone 21-(hydrogen succinate) ChemIDplus prednisolone 21-hemisuccinate ChemIDplus prednisolone 21-succinate ChemIDplus prednisolone bisuccinate ChemIDplus prednisolone hemisuccinate ChemIDplus Brand Name Source Prednisolut ChemIDplus Manual Xrefs Databases 2246 DrugCentral D02156 KEGG DRUG DB14633 DrugBank LSM-36396 LINCS View more database links Registry Number Type Source 2920-86-7 CAS Registry Number ChemIDplus Citations Types Sources 1029643 PubMed citation Europe PMC 10959575 PubMed citation Europe PMC 11446168 PubMed citation Europe PMC 1235505 PubMed citation Europe PMC 13371916 PubMed citation Europe PMC 13439215 PubMed citation Europe PMC 13704303 PubMed citation Europe PMC 13822491 PubMed citation Europe PMC 14483331 PubMed citation Europe PMC 2253583 PubMed citation Europe PMC 29175410 PubMed citation Europe PMC 3213042 PubMed citation Europe PMC 3441354 PubMed citation Europe PMC 3580023 PubMed citation Europe PMC 3964328 PubMed citation Europe PMC 3994138 PubMed citation Europe PMC 4084667 PubMed citation Europe PMC 4433653 PubMed citation Europe PMC Last Modified 23 October 2020