4-hydroxy-TEMPO (CHEBI:180664)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	4-hydroxy-TEMPO

ChEBI ID	CHEBI:180664

Definition	A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Johannes Hunold (ORCID: 0000-0002-4378-6061)

Supplier Information

Download	Molfile XML SDF

Wikipedia	License

Read full article at Wikipedia

Formula

C9H18NO2

Net Charge

Average Mass

172.245

Monoisotopic Mass

172.13375

InChI

InChI=1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3

InChIKey

UZFMOKQJFYMBGY-UHFFFAOYSA-N

SMILES

CC1(C)CC(O)CC(C)(C)N1[O]

Roles Classification
Chemical Role(s):	radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. catalyst A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.

Biological Role(s):	apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

Application(s):	nephroprotective agent Any protective agent that is able to prevent damage to the kidney. anti-inflammatory agent Any compound that has anti-inflammatory effects. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. hepatoprotective agent Any compound that is able to prevent damage to the liver. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	4-hydroxy-TEMPO (CHEBI:180664) has functional parent TEMPO (CHEBI:32849) 4-hydroxy-TEMPO (CHEBI:180664) has role anti-inflammatory agent (CHEBI:67079) 4-hydroxy-TEMPO (CHEBI:180664) has role antineoplastic agent (CHEBI:35610) 4-hydroxy-TEMPO (CHEBI:180664) has role apoptosis inducer (CHEBI:68495) 4-hydroxy-TEMPO (CHEBI:180664) has role catalyst (CHEBI:35223) 4-hydroxy-TEMPO (CHEBI:180664) has role hepatoprotective agent (CHEBI:62868) 4-hydroxy-TEMPO (CHEBI:180664) has role nephroprotective agent (CHEBI:76595) 4-hydroxy-TEMPO (CHEBI:180664) has role neuroprotective agent (CHEBI:63726) 4-hydroxy-TEMPO (CHEBI:180664) has role radical scavenger (CHEBI:48578) 4-hydroxy-TEMPO (CHEBI:180664) is a aminoxyls (CHEBI:39477) 4-hydroxy-TEMPO (CHEBI:180664) is a hydroxypiperidine (CHEBI:48590)

Incoming	4-hydroxy-TEMPO benzoate (CHEBI:180676) has functional parent 4-hydroxy-TEMPO (CHEBI:180664)

IUPAC Name

(4-hydroxy-2,2,6,6-tetramethylpiperidin-1-yl)oxidanyl

Synonyms	Sources
2,2,6,6-tetramethyl-1-oxy-4-hydroxypiperidine	ChEBI
2,2,6,6-tetramethyl-4-hydroxypiperidin-1-oxyl	ChemIDplus
2,2,6,6-tetramethyl-4-hydroxypiperidine 1-oxide radical	ChEBI
2,2,6,6-tetramethyl-4-hydroxypiperidine-1-oxyl	ChEBI
2,2,6,6-tetramethyl-4-hydroxypiperidinooxy	ChemIDplus
2,2,6,6-tetramethyl-4-hydroxypiperidinooxy radical	ChemIDplus
2,2,6,6-tetramethyl-4-hydroxypiperidyl 1-oxyl	ChemIDplus
2,2,6,6-tetramethyl-4-oxypiperidine-1-oxyl	ChemIDplus
2,2,6,6-tetramethyl-4-piperidinol 1-oxide	ChemIDplus
2,2,6,6-tetramethyl-4-piperidinol 1-oxyl	ChemIDplus
2,2,6,6-tetramethyl-4-piperidinol N-oxyl	ChemIDplus
2,2,6,6-tetramethyl-4-piperidinol nitroxide	ChemIDplus
2,2,6,6-tetramethyl-4-piperidinol-1-oxy	ChemIDplus
2,2,6,6-tetramethyl-4-piperidinol-1-oxyl radical	ChEBI
2,2,6,6-tetramethylpiperidine-N-oxyl-4-ol	ChemIDplus
4-hydroxy-2,2,6,6-tetramethyl-1-piperidinoxyl	ChEBI
4-hydroxy-2,2,6,6-tetramethyl-1-piperidinyloxy	ChemIDplus
4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl	ChEBI
4-hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl	ChemIDplus
4-hydroxy-2,2,6,6-tetramethylpiperidine N-oxide	ChemIDplus
4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl	ChemIDplus
4-hydroxy-2,2,6,6-tetramethylpiperidinooxy	ChemIDplus
4-hydroxy-2,2,6,6-tetramethylpiperidinooxy radical	ChemIDplus
4-hydroxy-2,2,6,6-tetramethylpiperidinyloxyl	ChEBI
4-hydroxy-TEMPO free radical	ChEBI
4-OH-TEMPO	SUBMITTER
HyTEMPO	ChEBI
Tanol	ChemIDplus
TEMPOL	ChemIDplus
TMPN	ChemIDplus

Last Modified

18 November 2021