CHEBI:10098 - Z-Phe-Phe-CHN2

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ChEBI Name Z-Phe-Phe-CHN2
ChEBI ID CHEBI:10098
ChEBI ASCII Name Z-Phe-Phe-CHN2
Definition A diazo compound that is L-phenylalanyl-L-phenylalanine in which the amino group is protected by a (benzyloxy)carbonyl group and the carboxy group is substituted by a diazoacetyl group. It is a cathepsin L inhibitor.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C27H26N4O4
Net Charge 0
Average Mass 470.529
Monoisotopic Mass 470.19541
InChI InChI=1S/C27H26N4O4/c28-29-18-25(32)23(16-20-10-4-1-5-11-20)30-26(33)24(17-21-12-6-2-7-13-21)31-27(34)35-19-22-14-8-3-9-15-22/h1-15,18,23-24H,16-17,19H2,(H,30,33)(H,31,34)/t23-,24-/m0/s1
InChIKey JIFSOVRQDDYNAH-ZEQRLZLVSA-N
SMILES [N-]=[N+]=CC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CC=CC=C1
Roles Classification
Biological Role(s): cathepsin L (EC 3.4.22.15) inhibitor
An EC 3.4.22.* (cysteine endopeptidase) inhibitor which interferes with the action of cathepsin L (EC 3.4.22.15).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing Z-Phe-Phe-CHN2 (CHEBI:10098) has role cathepsin L (EC 3.4.22.15) inhibitor (CHEBI:70821)
Z-Phe-Phe-CHN2 (CHEBI:10098) is a L-phenylalanine derivative (CHEBI:84144)
Z-Phe-Phe-CHN2 (CHEBI:10098) is a carboxylic ester (CHEBI:33308)
Z-Phe-Phe-CHN2 (CHEBI:10098) is a diazo compound (CHEBI:39444)
Z-Phe-Phe-CHN2 (CHEBI:10098) is a secondary carboxamide (CHEBI:140325)
IUPAC Name
Nα-[(benzyloxy)carbonyl]-N-[(2S)-4-diazo-3-oxo-1-phenylbutan-2-yl]-L-phenylalaninamide
Synonyms Sources
benzyloxycarbonyl-phenylalanine-phenylalanine-diazomethane ChEBI
Z-FF-DMK ChEBI
Z-L-Phe-L-Phe-CHN2 ChEBI
Z-Phe-Phe-CHN2 KEGG COMPOUND
Z-Phe-Phe-diazomethylketone ChEBI
Manual Xref Database
C02202 KEGG COMPOUND
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Registry Number Type Source
65178-14-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
18 January 2024