Services
Research
Training
Industry
About us
ChEBI
Examples:
iron*
,
InChI=1S/CH4O/c1-2/h2H,1H3
,
caffeine
Advanced
Home
Advanced Search
Browse
Documentation
Download
Tools
About ChEBI
Submit
Contact us
DiNA
Statistics
Entity of the Month
Periodic Table
Ontology
Train online
User Manual
Annotation Manual
Developer Manual
FAQ's
BiNChE
libChEBI
Web Services
ChEBI
> Main
CHEBI:43996 - mitoguazone
Main
ChEBI Ontology
Automatic Xrefs
Reactions
Pathways
Models
ChEBI Name
mitoguazone
ChEBI ID
CHEBI:43996
Definition
A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
XML
SDF
Find compounds which contain this structure
Find compounds which resemble this structure
Take structure to the Advanced Search
more structures >>
Molfile
expand
Wikipedia
License
Read full article at Wikipedia
Formula
C5H12N8
Net Charge
0
Average Mass
184.20240
Monoisotopic Mass
184.11849
InChI
InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+
InChIKey
MXWHMTNPTTVWDM-NXOFHUPFSA-N
SMILES
C\C(\C=N\NC(N)=N)=N/NC(N)=N
Roles Classification
Biological Role
(s):
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of adenosylmethionine decarboxylase (EC 4.1.1.50).
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
mitoguazone (
CHEBI:43996
)
has functional parent
aminoguanidine (
CHEBI:40618
)
mitoguazone (
CHEBI:43996
)
has functional parent
methylglyoxal (
CHEBI:17158
)
mitoguazone (
CHEBI:43996
)
has role
antineoplastic agent (
CHEBI:35610
)
mitoguazone (
CHEBI:43996
)
has role
apoptosis inducer (
CHEBI:68495
)
mitoguazone (
CHEBI:43996
)
has role
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor (
CHEBI:78024
)
mitoguazone (
CHEBI:43996
)
is a
guanidines (
CHEBI:24436
)
mitoguazone (
CHEBI:43996
)
is a
hydrazone (
CHEBI:38532
)
mitoguazone (
CHEBI:43996
)
is conjugate base of
mitoguazone(2+) (
CHEBI:78025
)
Incoming
mitoguazone(2+) (
CHEBI:78025
)
is conjugate acid of
mitoguazone (
CHEBI:43996
)
INNs
Sources
mitoguazona
ChemIDplus
mitoguazone
ChemIDplus
mitoguazone
WHO MedNet
mitoguazonum
ChemIDplus
Synonyms
Sources
Me-GAG
ChemIDplus
Methyl-Gag
ChemIDplus
Methylglyoxal bis(amidinohydrazone)
ChemIDplus
Methylglyoxal bis(guanylhydrazone)
ChemIDplus
MGBG
MetaCyc
Pyruvaldehyde bis(amidinohydrazone)
ChemIDplus
Manual Xrefs
Databases
3362
DrugCentral
CPD0-1398
MetaCyc
D07258
KEGG DRUG
MGB
PDBeChem
Mitoguazone
Wikipedia
View more database links
Registry Numbers
Types
Sources
1912591
Reaxys Registry Number
Reaxys
459-86-9
CAS Registry Number
ChemIDplus
Citations
Types
Sources
10706462
PubMed citation
Europe PMC
12906902
PubMed citation
Europe PMC
14533444
PubMed citation
Europe PMC
15541750
PubMed citation
Europe PMC
2292054
PubMed citation
Europe PMC
2395900
PubMed citation
Europe PMC
2655552
PubMed citation
Europe PMC
3614816
PubMed citation
Europe PMC
3909804
PubMed citation
Europe PMC
436119
PubMed citation
Europe PMC
6469501
PubMed citation
Europe PMC
6616496
PubMed citation
Europe PMC
6678871
PubMed citation
Europe PMC
6831474
PubMed citation
Europe PMC
6844733
PubMed citation
Europe PMC
7044533
PubMed citation
Europe PMC
7083245
PubMed citation
Europe PMC
7237449
PubMed citation
Europe PMC
7237467
PubMed citation
Europe PMC
869671
PubMed citation
Europe PMC
8913846
PubMed citation
Europe PMC
9215963
PubMed citation
Europe PMC
9711922
PubMed citation
Europe PMC
9773808
PubMed citation
Europe PMC
Last Modified
22 February 2017