CHEBI:5721 - hinokiflavone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name hinokiflavone
ChEBI ID CHEBI:5721
Definition A biflavonoid that is apigenin substituted by a 4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy group at position 6. A diflavonyl ether, it is isolated from Rhus succedanea and has been found to possess significant cytotoxic potential.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:66014
Supplier Information
Download Molfile XML SDF
Formula C30H18O10
Net Charge 0
Average Mass 538.45790
Monoisotopic Mass 538.09000
InChI InChI=1S/C30H18O10/c31-16-5-1-14(2-6-16)24-12-21(35)28-26(40-24)13-22(36)30(29(28)37)38-18-7-3-15(4-8-18)23-11-20(34)27-19(33)9-17(32)10-25(27)39-23/h1-13,31-33,36-37H
InChIKey WTDHMFBJQJSTMH-UHFFFAOYSA-N
SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)c(Oc3ccc(cc3)-c3cc(=O)c4c(O)cc(O)cc4o3)c(O)cc2o1
Metabolite of Species Details
Rhus succedanea (NCBI:txid269721) Found in fruit (BTO:0000486). drupes See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing hinokiflavone (CHEBI:5721) has functional parent apigenin (CHEBI:18388)
hinokiflavone (CHEBI:5721) has role antineoplastic agent (CHEBI:35610)
hinokiflavone (CHEBI:5721) has role metabolite (CHEBI:25212)
hinokiflavone (CHEBI:5721) has role neuroprotective agent (CHEBI:63726)
hinokiflavone (CHEBI:5721) is a aromatic ether (CHEBI:35618)
hinokiflavone (CHEBI:5721) is a biflavonoid (CHEBI:50128)
hinokiflavone (CHEBI:5721) is a hydroxyflavone (CHEBI:24698)
IUPAC Name
6-[4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Synonyms Sources
4',6''-O-biapigenin ChemIDplus
Hinokiflavone KEGG COMPOUND
Manual Xrefs Databases
C00001049 KNApSAcK
C10057 KEGG COMPOUND
EP1245230 Patent
LMPK12040004 LIPID MAPS
WO9700679 Patent
View more database links
Registry Numbers Types Sources
19202-36-9 CAS Registry Number ChemIDplus
379316 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
10532874 PubMed citation Europe PMC
17340268 PubMed citation Europe PMC
2526343 PubMed citation Europe PMC
5977959 PubMed citation Europe PMC
Last Modified
28 July 2014