CHEBI:6924 - miconazole nitrate

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name miconazole nitrate
ChEBI ID CHEBI:6924
Definition A racemate composed of equimolar amounts of (R)- and (S)-miconazole nitrate. An antifungal used for the treatment of athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Stars This entity has been manually annotated by the ChEBI Team.
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formulae C18H14Cl4N2O.HNO3
C18H15Cl4N3O4
Net Charge 0
Average Mass 479.14100
Monoisotopic Mass 476.98167
Roles Classification
Biological Role(s): antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via imidazole antifungal agent )
(via conazole antifungal agent )
ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
(via conazole antifungal agent )
glucocorticoid receptor antagonist
An antagonist that binds to and deactivates glucocorticoid receptors.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing miconazole nitrate (CHEBI:6924) has part (R)-miconazole nitrate (CHEBI:82886)
miconazole nitrate (CHEBI:6924) has part (S)-miconazole nitrate (CHEBI:82888)
miconazole nitrate (CHEBI:6924) has part miconazole (CHEBI:6923)
miconazole nitrate (CHEBI:6924) has role antifungal agent (CHEBI:35718)
miconazole nitrate (CHEBI:6924) has role antineoplastic agent (CHEBI:35610)
miconazole nitrate (CHEBI:6924) has role ergosterol biosynthesis inhibitor (CHEBI:75282)
miconazole nitrate (CHEBI:6924) has role glucocorticoid receptor antagonist (CHEBI:82891)
miconazole nitrate (CHEBI:6924) is a conazole antifungal drug (CHEBI:87071)
miconazole nitrate (CHEBI:6924) is a imidazole antifungal drug (CHEBI:87069)
miconazole nitrate (CHEBI:6924) is a racemate (CHEBI:60911)
IUPAC Name
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate
Synonyms Sources
(±)-miconazole nitrate ChEBI
(RS)-miconazole nitrate ChEBI
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole mononitrate ChemIDplus
rac-miconazole nitrate ChEBI
Manual Xrefs Databases
C08070 KEGG COMPOUND
D00882 KEGG DRUG
DB01110 DrugBank
Miconazole Wikipedia
View more database links
Registry Numbers Types Sources
22832-87-7 CAS Registry Number KEGG COMPOUND
22832-87-7 CAS Registry Number ChemIDplus
4225531 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
22172026 PubMed citation Europe PMC
22407005 PubMed citation Europe PMC
22566173 PubMed citation Europe PMC
22585373 PubMed citation Europe PMC
22879356 PubMed citation Europe PMC
23263811 PubMed citation Europe PMC
23557492 PubMed citation Europe PMC
23675632 PubMed citation Europe PMC
23781847 PubMed citation Europe PMC
24455998 PubMed citation Europe PMC
24479833 PubMed citation Europe PMC
24505925 PubMed citation Europe PMC
24528709 PubMed citation Europe PMC
24645507 PubMed citation Europe PMC
24741805 PubMed citation Europe PMC
24750864 PubMed citation Europe PMC
Last Modified
22 July 2015