streptokordin (CHEBI:66524)

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ChEBI Name	streptokordin

ChEBI ID	CHEBI:66524

Definition	A pyridone that is pyridin-2(1H)-one substituted by an acetyl group at position 4 and a methyl group at position 6. It is isolated from the fermentation broth of Streptomyces sp. KORDI-3238 and exhibits moderate cytotoxicity against a number of human cancer cell lines.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C8H9NO2

Net Charge

Average Mass

151.16260

Monoisotopic Mass

151.06333

InChI

InChI=1S/C8H9NO2/c1-5-3-7(6(2)10)4-8(11)9-5/h3-4H,1-2H3,(H,9,11)

InChIKey

JCPDZXJDYRLFMC-UHFFFAOYSA-N

SMILES

CC(=O)c1cc(C)[nH]c(=O)c1

Metabolite of Species	Details
Streptomyces sp. (NCBI:txid1931)	of strain KORDI 3238 See: PubMed

Roles Classification
Biological Role(s):	antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	streptokordin (CHEBI:66524) has role antimicrobial agent (CHEBI:33281) streptokordin (CHEBI:66524) has role antineoplastic agent (CHEBI:35610) streptokordin (CHEBI:66524) has role metabolite (CHEBI:25212) streptokordin (CHEBI:66524) is a aromatic ketone (CHEBI:76224) streptokordin (CHEBI:66524) is a methyl ketone (CHEBI:51867) streptokordin (CHEBI:66524) is a pyridone (CHEBI:38183)

IUPAC Name

4-acetyl-6-methylpyridin-2(1H)-one

Synonym	Source
4-acetyl-6-methyl-1H-pyridine-2-one	ChEBI

Registry Number	Type	Source
10530579	Reaxys Registry Number	Reaxys

Citation	Type	Source
16830891	PubMed citation	Europe PMC

Last Modified

07 November 2013