pralidoxime (CHEBI:8354)

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ChEBI Name	pralidoxime

ChEBI ID	CHEBI:8354

Definition	A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C7H9N2O

Net Charge

Average Mass

137.15924

Monoisotopic Mass

137.07094

InChI

InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1

InChIKey

JBKPUQTUERUYQE-UHFFFAOYSA-O

SMILES

C[n+]1ccccc1\C=N\O

Roles Classification
Biological Role(s):	cholinergic drug Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. cholinesterase reactivator A drug used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates.

Application(s):	cholinergic drug Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. antidote to organophosphate poisoning A role borne by a molecule that acts to counteract or neutralise the deleterious effects of organophosphates or acetylcholinesterase inhibitors (nerve agents). antidote to sarin poisoning A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.

ChEBI Ontology
Outgoing	pralidoxime (CHEBI:8354) has role antidote to organophosphate poisoning (CHEBI:90753) pralidoxime (CHEBI:8354) has role antidote to sarin poisoning (CHEBI:136860) pralidoxime (CHEBI:8354) has role cholinergic drug (CHEBI:38323) pralidoxime (CHEBI:8354) has role cholinesterase reactivator (CHEBI:50241) pralidoxime (CHEBI:8354) is a pyridinium ion (CHEBI:50334)

Incoming	pralidoxime chloride (CHEBI:8355) has part pralidoxime (CHEBI:8354) pralidoxime iodide (CHEBI:32038) has part pralidoxime (CHEBI:8354) pralidoxime mesylate (CHEBI:50240) has part pralidoxime (CHEBI:8354)

IUPAC Name

2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium

INN	Source
pralidoxime	ChemIDplus

Citation	Type	Source
24625936	PubMed citation	Europe PMC

Last Modified

30 September 2021