4849F (CHEBI:65910)

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ChEBI Name	4849F

ChEBI ID	CHEBI:65910

Definition	An azaarene that is benzo[c]cinnoline with methoxy substituents at positions 1 and 10. It is isolated from Streptomyces sp. strain 4849 with pharmaceutical potential as an inhibitor of interleukin-4 receptor (IL-4).

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C14H12N2O2

Net Charge

Average Mass

240.25730

Monoisotopic Mass

240.08988

InChI

InChI=1S/C14H12N2O2/c1-17-11-7-3-5-9-13(11)14-10(16-15-9)6-4-8-12(14)18-2/h3-8H,1-2H3

InChIKey

DKHBOZGVMLZLLL-UHFFFAOYSA-N

SMILES

COc1cccc2nnc3cccc(OC)c3c12

Metabolite of Species	Details
Streptomyces sp. (NCBI:txid1931)	of strain 4849 See: PubMed

Roles Classification
Biological Role(s):	antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

ChEBI Ontology
Outgoing	4849F (CHEBI:65910) has role antimicrobial agent (CHEBI:33281) 4849F (CHEBI:65910) has role metabolite (CHEBI:25212) 4849F (CHEBI:65910) is a aromatic ether (CHEBI:35618) 4849F (CHEBI:65910) is a azaarene (CHEBI:50893) 4849F (CHEBI:65910) is a organic heterotricyclic compound (CHEBI:26979)

IUPAC Name

1,10-dimethoxybenzo[c]cinnoline

Citation	Type	Source
17551212	PubMed citation	Europe PMC

Last Modified

25 September 2012