CHEBI:65490 - BF 6

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ChEBI Name BF 6
ChEBI ID CHEBI:65490
Definition An organic heterotetracyclic compound that is 8,12-dihydro-2H,9H-pyrano[2,3-a]xanthene-4,9,11(3H,10H)-trione substituted by methyl groups at positions 6, 8, 8, 10 and 10 and phenyl groups at positions 2 and 12 respectively (the S-enantiomer). It is isolated from the leaves of Baeckea frutescens and exhibits cytotoxicity against leukemia cells.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C33H30O6
Net Charge 0
Average Mass 522.58770
Monoisotopic Mass 522.20424
InChI InChI=1S/C33H30O6/c1-17-26(35)23-20(34)16-21(18-12-8-6-9-13-18)38-28(23)24-22(19-14-10-7-11-15-19)25-29(36)32(2,3)31(37)33(4,5)30(25)39-27(17)24/h6-15,21-22,35H,16H2,1-5H3/t21-,22?/m0/s1
InChIKey XFYRJHANHCHCTK-HMTLIYDFSA-N
SMILES Cc1c(O)c2C(=O)C[C@H](Oc2c2C(c3ccccc3)C3=C(Oc12)C(C)(C)C(=O)C(C)(C)C3=O)c1ccccc1
Metabolite of Species Details
Baeckea frutescens (NCBI:txid199392) Found in leaf (BTO:0000713). See: DOI
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing BF 6 (CHEBI:65490) has role antineoplastic agent (CHEBI:35610)
BF 6 (CHEBI:65490) has role metabolite (CHEBI:25212)
BF 6 (CHEBI:65490) is a extended flavonoid (CHEBI:71037)
BF 6 (CHEBI:65490) is a organic heterotetracyclic compound (CHEBI:38163)
BF 6 (CHEBI:65490) is a phenols (CHEBI:33853)
IUPAC Name
(2S)-5-hydroxy-6,8,8,10,10-pentamethyl-2,12-diphenyl-8,12-dihydro-2H,9H-pyrano[2,3-a]xanthene-4,9,11(3H,10H)-trione
Synonym Source
Baeckea frutescens 6 ChEBI
Last Modified
20 November 2012
General Comment
2012-11-20 Phytochemistry 1999, 50, 273-277.