CHEBI:82717 - tedizolid

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ChEBI Name tedizolid
ChEBI ID CHEBI:82717
Definition A member of the class of pyridines that is pyridine which is substituted by a 2-methyl-2H-tetrazol-5-yl group at position 2 and by a 2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl group at position 5. It is used as its phosphate pro-drug used for the treatment of acute bacterial skin and skin structure infections caused by certain susceptible bacteria, including Staphylococcus aureus (including methicillin-resistant strains (MRSA) and methicillin-susceptible strains), various Streptococcus species, and Enterococcus faecalis.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Toni Morrison
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Formula C17H15FN6O3
Net Charge 0
Average Mass 370.338
Monoisotopic Mass 370.11897
InChI InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1
InChIKey XFALPSLJIHVRKE-GFCCVEGCSA-N
SMILES C1=C(C=CC(=C1F)C2=CN=C(C=C2)C=3N=NN(N3)C)N4C(O[C@H](C4)CO)=O
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
drug metabolite

protein synthesis inhibitor
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
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ChEBI Ontology
Outgoing tedizolid (CHEBI:82717) has role antimicrobial agent (CHEBI:33281)
tedizolid (CHEBI:82717) has role drug metabolite (CHEBI:49103)
tedizolid (CHEBI:82717) has role protein synthesis inhibitor (CHEBI:48001)
tedizolid (CHEBI:82717) is a carbamate ester (CHEBI:23003)
tedizolid (CHEBI:82717) is a organofluorine compound (CHEBI:37143)
tedizolid (CHEBI:82717) is a oxazolidinone (CHEBI:55374)
tedizolid (CHEBI:82717) is a primary alcohol (CHEBI:15734)
tedizolid (CHEBI:82717) is a pyridines (CHEBI:26421)
tedizolid (CHEBI:82717) is a tetrazoles (CHEBI:35689)
IUPAC Name
(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one
INN Source
tedizolid KEGG DRUG
Synonyms Sources
DA 7157 ChemIDplus
DA-7157 ChemIDplus
Torezolid ChemIDplus
TR 700 ChemIDplus
TR-700 ChemIDplus
Manual Xrefs Databases
D09685 KEGG DRUG
Tedizolid Wikipedia
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Registry Numbers Types Sources
10589936 Reaxys Registry Number Reaxys
856866-72-3 CAS Registry Number KEGG DRUG
856866-72-3 CAS Registry Number ChemIDplus
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Last Modified
15 July 2016