CHEBI:65457 - astragaloside IV

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ChEBI Name astragaloside IV
ChEBI ID CHEBI:65457
Definition A pentacyclic triterpenoid that is cycloastragenol having β-D-xylopyranosyl and β-D-glucopyranosyl residues attached at positions O-3 and O-6 respectively. It is isolated from Astragalus membranaceus var mongholicus.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C41H68O14
Net Charge 0
Average Mass 784.97020
Monoisotopic Mass 784.46091
InChI InChI=1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1
InChIKey QMNWISYXSJWHRY-YLNUDOOFSA-N
SMILES [H][C@]1(OC[C@@H](O)[C@H](O)[C@H]1O)O[C@H]1CC[C@]23C[C@]22CC[C@]4(C)[C@]([H])([C@@H](O)C[C@@]4(C)[C@]2([H])C[C@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@]3([H])C1(C)C)[C@@]1(C)CC[C@H](O1)C(C)(C)O
Metabolite of Species Details
Astragalus membranaceus (NCBI:txid649199) Found in root (BTO:0001188). See: DOI
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
EC 4.2.1.1 (carbonic anhydrase) inhibitor
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via saponin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
pro-angiogenic agent
Any compound that promotes the growth of new blood vessels from pre-existing vessels.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing astragaloside IV (CHEBI:65457) has functional parent cycloastragenol (CHEBI:71314)
astragaloside IV (CHEBI:65457) has role anti-inflammatory agent (CHEBI:67079)
astragaloside IV (CHEBI:65457) has role antioxidant (CHEBI:22586)
astragaloside IV (CHEBI:65457) has role EC 4.2.1.1 (carbonic anhydrase) inhibitor (CHEBI:23018)
astragaloside IV (CHEBI:65457) has role neuroprotective agent (CHEBI:63726)
astragaloside IV (CHEBI:65457) has role plant metabolite (CHEBI:76924)
astragaloside IV (CHEBI:65457) has role pro-angiogenic agent (CHEBI:72571)
astragaloside IV (CHEBI:65457) is a pentacyclic triterpenoid (CHEBI:25872)
astragaloside IV (CHEBI:65457) is a triterpenoid saponin (CHEBI:61778)
Synonyms Sources
3-O-β-D-xylopyranosyl-6-O-β-D-glucopyranosylcycloastragenol ChEBI
Astragaloside A ChemIDplus
Cyclosiversioside F ChemIDplus
Registry Numbers Types Sources
5720375 Reaxys Registry Number Reaxys
83207-58-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
16 January 2014