CHEBI:144949 - NSC 23766 trihydrochloride

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ChEBI Name NSC 23766 trihydrochloride
ChEBI ID CHEBI:144949
Definition A hydrochloride resulting from the formal reaction of NSC 23766 with 3 mol eq. of hydrogen chloride. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Sabrina Toro
Supplier Information
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Formula C24H35N7.ClH.ClH.ClH
Net Charge 0
Average Mass 530.970
Monoisotopic Mass 529.22543
InChI InChI=1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30);3*1H
InChIKey CPUHORIUXPQCHW-UHFFFAOYSA-N
SMILES CC(CCCN(CC)CC)NC1=NC(=CC(NC2=CC=3C(=NC(=CC3N)C)C=C2)=N1)C.Cl.Cl.Cl
Roles Classification
Biological Role(s): EC 3.6.5.2 (small monomeric GTPase) inhibitor
Any EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor that interferes with the action of small monomeric GTPase (EC 3.6.5.2).
antiviral agent
A substance that destroys or inhibits replication of viruses.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
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ChEBI Ontology
Outgoing NSC 23766 trihydrochloride (CHEBI:144949) has part NSC 23766 (CHEBI:144984)
NSC 23766 trihydrochloride (CHEBI:144949) has role antiviral agent (CHEBI:22587)
NSC 23766 trihydrochloride (CHEBI:144949) has role apoptosis inducer (CHEBI:68495)
NSC 23766 trihydrochloride (CHEBI:144949) has role EC 3.6.5.2 (small monomeric GTPase) inhibitor (CHEBI:144981)
NSC 23766 trihydrochloride (CHEBI:144949) has role muscarinic antagonist (CHEBI:48876)
NSC 23766 trihydrochloride (CHEBI:144949) is a hydrochloride (CHEBI:36807)
IUPAC Name
N6-(2-{[5-(diethylamino)pentan-2-yl]amino}-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride
Synonyms Sources
NSC 23766·3HCl SUBMITTER
NSC-23766·3HCl ChEBI
NSC23766·3HCl ChEBI
Registry Number Type Source
1177865-17-6 CAS Registry Number SUBMITTER
Last Modified
26 September 2019