CHEBI:8654 - pyrantel

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name pyrantel ChEBI ID CHEBI:8654 Definition A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C11H14N2S Net Charge 0 Average Mass 206.30700 Monoisotopic Mass 206.08777 InChI InChI=1S/C11H14N2S/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h2,4-6,9H,3,7-8H2,1H3/b6-5+ InChIKey YSAUAVHXTIETRK-AATRIKPKSA-N SMILES CN1CCCN=C1\C=C\c1cccs1 Roles Classification Application(s): antinematodal drug A substance used in the treatment or control of nematode infestations. View more via ChEBI Ontology ChEBI Ontology Outgoing pyrantel (CHEBI:8654) has role antinematodal drug (CHEBI:35444) pyrantel (CHEBI:8654) is a 1,4,5,6-tetrahydropyrimidines (CHEBI:78715) pyrantel (CHEBI:8654) is a carboxamidine (CHEBI:35359) pyrantel (CHEBI:8654) is a thiophenes (CHEBI:26961) IUPAC Name 1-methyl-2-[(E)-2-(2-thienyl)vinyl]-1,4,5,6-tetrahydropyrimidine INNs Sources pirantel WHO MedNet pyrantel WHO MedNet pyrantel ChemIDplus pyrantelum WHO MedNet Manual Xrefs Databases 2999 DrugCentral BE658987 Patent C07409 KEGG COMPOUND D08451 KEGG DRUG Pyrantel Wikipedia US3502661 Patent View more database links Registry Numbers Types Sources 15686-83-6 CAS Registry Number KEGG COMPOUND 15686-83-6 CAS Registry Number ChemIDplus 518505 Reaxys Registry Number Reaxys Citations Types Sources 20307935 PubMed citation Europe PMC 21689886 PubMed citation Europe PMC 2619378 PubMed citation Europe PMC 5124439 PubMed citation Europe PMC 552733 PubMed citation Europe PMC 7402460 PubMed citation Europe PMC Last Modified 22 February 2017