CHEBI:66527 - strongylophorine-26

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ChEBI Name strongylophorine-26
ChEBI ID CHEBI:66527
Definition A diterpenoid that is 15,17-epoxypodocarpan-15-one substituted by a hydroxy group at position 13, methyl groups at positions 8 and 13 and a (5-methoxy-3,6-dioxocyclohexa-1,4-dien-1-yl)methyl group at position 14 (the 13α,14β stereoisomer). Isolated from the marine sponge Petrosia corticata, it exhibits antineoplastic activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C27H36O6
Net Charge 0
Average Mass 456.57110
Monoisotopic Mass 456.25119
InChI InChI=1S/C27H36O6/c1-24-10-6-20-25(2)8-5-9-27(20,15-33-23(25)30)19(24)7-11-26(3,31)21(24)13-16-12-17(28)14-18(32-4)22(16)29/h12,14,19-21,31H,5-11,13,15H2,1-4H3/t19-,20-,21-,24+,25-,26-,27-/m0/s1
InChIKey AMOGVPDDGBDGJG-FOMYWIRZSA-N
SMILES [H][C@]12CC[C@](C)(O)[C@@H](CC3=CC(=O)C=C(OC)C3=O)[C@]1(C)CC[C@@]1([H])[C@]3(C)CCC[C@]21COC3=O
Metabolite of Species Details
Petrosia corticata (WORMS:166869) Lipophilic extract of the marine sponge Petrosia (Strongylophora) corticata See: PubMed
Roles Classification
Biological Role(s): animal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
marine metabolite
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via meroterpenoid )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing strongylophorine-26 (CHEBI:66527) has role animal metabolite (CHEBI:75767)
strongylophorine-26 (CHEBI:66527) has role antineoplastic agent (CHEBI:35610)
strongylophorine-26 (CHEBI:66527) has role marine metabolite (CHEBI:76507)
strongylophorine-26 (CHEBI:66527) is a γ-lactone (CHEBI:37581)
strongylophorine-26 (CHEBI:66527) is a p-quinones (CHEBI:25830)
strongylophorine-26 (CHEBI:66527) is a diterpenoid (CHEBI:23849)
strongylophorine-26 (CHEBI:66527) is a enol ether (CHEBI:47985)
strongylophorine-26 (CHEBI:66527) is a meroterpenoid (CHEBI:64419)
strongylophorine-26 (CHEBI:66527) is a tertiary alcohol (CHEBI:26878)
IUPAC Name
2-{[(13α,14β)-13-hydroxy-8,13-dimethyl-15-oxo-15,17-epoxypodocarpan-14-yl]methyl}-6-methoxycyclohexa-2,5-diene-1,4-dione
Registry Number Type Source
10738211 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
15332859 PubMed citation Europe PMC
15897241 PubMed citation Europe PMC
17407351 PubMed citation Europe PMC
Last Modified
06 June 2016