colpol (CHEBI:65652)

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ChEBI Name	colpol

ChEBI ID	CHEBI:65652

Definition	An organobromine compound that is 2-bromobenzene-1,3-diol substituted at position 5 by a (2Z)-4-(4-bromo-2-hydroxy-5-methoxyphenyl)but-2-en-1-yl group. It is isolated from the Red Sea alga Colpomenia sinuosa and exhibits cytotoxicity towards P388, A549, HT-29 and CV-1 tumor cells.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C17H16Br2O4

Net Charge

Average Mass

444.11500

Monoisotopic Mass

441.94153

InChI

InChI=1S/C17H16Br2O4/c1-23-16-8-11(13(20)9-12(16)18)5-3-2-4-10-6-14(21)17(19)15(22)7-10/h2-3,6-9,20-22H,4-5H2,1H3/b3-2-

InChIKey

NHRGNEKFTRCLID-IHWYPQMZSA-N

SMILES

COc1cc(C\C=C/Cc2cc(O)c(Br)c(O)c2)c(O)cc1Br

Metabolite of Species	Details
Colpomenia sinuosa (NCBI:txid87236)	See: DOI

Roles Classification
Biological Role(s):	metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	colpol (CHEBI:65652) has role antineoplastic agent (CHEBI:35610) colpol (CHEBI:65652) has role metabolite (CHEBI:25212) colpol (CHEBI:65652) is a aromatic ether (CHEBI:35618) colpol (CHEBI:65652) is a organobromine compound (CHEBI:37141) colpol (CHEBI:65652) is a polyphenol (CHEBI:26195)

IUPAC Name

2-bromo-5-[(2Z)-4-(4-bromo-2-hydroxy-5-methoxyphenyl)but-2-en-1-yl]benzene-1,3-diol

Last Modified

13 December 2012

General Comment
2012-12-13	J. Nat. Prod. (1993), 56, 1201.