CHEBI:77319 - oltipraz

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ChEBI Name oltipraz
ChEBI ID CHEBI:77319
Definition A 1,2-dithiole that is 3H-1,2-dithiole-3-thione substituted at positions 4 and 5 by methyl and pyrazin-2-yl groups respectively.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C8H6N2S3
Net Charge 0
Average Mass 226.34200
Monoisotopic Mass 225.969
InChI InChI=1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
InChIKey CKNAQFVBEHDJQV-UHFFFAOYSA-N
SMILES Cc1c(ssc1=S)-c1cnccn1
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): antimutagen
An agent that reduces or interferes with the mutagenic actions or effects of a substance.
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins.
neurotoxin
A poison that interferes with the functions of the nervous system.
Application(s): angiogenesis modulating agent
An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
protective agent
Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
schistosomicide drug
Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma.
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ChEBI Ontology
Outgoing oltipraz (CHEBI:77319) has role angiogenesis modulating agent (CHEBI:50926)
oltipraz (CHEBI:77319) has role antimutagen (CHEBI:73190)
oltipraz (CHEBI:77319) has role antineoplastic agent (CHEBI:35610)
oltipraz (CHEBI:77319) has role antioxidant (CHEBI:22586)
oltipraz (CHEBI:77319) has role EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor (CHEBI:35608)
oltipraz (CHEBI:77319) has role neurotoxin (CHEBI:50910)
oltipraz (CHEBI:77319) has role protective agent (CHEBI:50267)
oltipraz (CHEBI:77319) has role schistosomicide drug (CHEBI:38941)
oltipraz (CHEBI:77319) is a 1,2-dithiole (CHEBI:48859)
oltipraz (CHEBI:77319) is a pyrazines (CHEBI:38314)
IUPAC Name
4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione
INNs Sources
oltipraz ChemIDplus
oltipraz WHO MedNet
oltipraz WHO MedNet
oltiprazum ChemIDplus
Synonyms Sources
4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione ChemIDplus
5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione ChemIDplus
RP 35972 ChemIDplus
RP-35,972 ChemIDplus
Manual Xrefs Databases
HMDB0041967 HMDB
Oltipraz Wikipedia
View more database links
Registry Numbers Types Sources
64224-21-1 CAS Registry Number ChemIDplus
978110 Beilstein Registry Number ChemIDplus
978110 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
07 March 2014