4-aminopyridine (CHEBI:34385)

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ChEBI Name	4-aminopyridine

ChEBI ID	CHEBI:34385

Definition	An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C5H6N2

Net Charge

Average Mass

94.11462

Monoisotopic Mass

94.05310

InChI

InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)

InChIKey

NUKYPUAOHBNCPY-UHFFFAOYSA-N

SMILES

Nc1ccncc1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	potassium channel blocker An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.

Application(s):	orphan drug Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease. avicide A substance used to destroy bird pests (class Aves).

ChEBI Ontology
Outgoing	4-aminopyridine (CHEBI:34385) has role avicide (CHEBI:33289) 4-aminopyridine (CHEBI:34385) has role orphan drug (CHEBI:71031) 4-aminopyridine (CHEBI:34385) has role potassium channel blocker (CHEBI:50509) 4-aminopyridine (CHEBI:34385) is a aminopyridine (CHEBI:38207) 4-aminopyridine (CHEBI:34385) is a aromatic amine (CHEBI:33860)

Incoming	4-aminonicotinic acid (CHEBI:68577) has functional parent 4-aminopyridine (CHEBI:34385) 4-aminopyridine-3-methanol (CHEBI:149772) has functional parent 4-aminopyridine (CHEBI:34385) torasemide (CHEBI:9637) has functional parent 4-aminopyridine (CHEBI:34385)

IUPAC Name

pyridin-4-amine

Brand Name	Source
Ampyra	KEGG DRUG

Last Modified

20 May 2020