CHEBI:77794 - (R)-temafloxacin

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ChEBI Name (R)-temafloxacin
ChEBI ID CHEBI:77794
ChEBI ASCII Name (R)-temafloxacin
Definition 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid that has R configuration.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C21H18F3N3O3
Net Charge 0
Average Mass 417.38110
Monoisotopic Mass 417.13003
InChI InChI=1S/C21H18F3N3O3/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30)/t11-/m1/s1
InChIKey QKDHBVNJCZBTMR-LLVKDONJSA-N
SMILES C[C@@H]1CN(CCN1)c1cc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via quinolone antibiotic )
(via heterocyclic antibiotic )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (R)-temafloxacin (CHEBI:77794) has role antibacterial drug (CHEBI:36047)
(R)-temafloxacin (CHEBI:77794) has role antiinfective agent (CHEBI:35441)
(R)-temafloxacin (CHEBI:77794) has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750)
(R)-temafloxacin (CHEBI:77794) is a 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CHEBI:77796)
(R)-temafloxacin (CHEBI:77794) is enantiomer of (S)-temafloxacin (CHEBI:77795)
Incoming temafloxacin (CHEBI:77788) has part (R)-temafloxacin (CHEBI:77794)
(S)-temafloxacin (CHEBI:77795) is enantiomer of (R)-temafloxacin (CHEBI:77794)
IUPAC Name
1-(2,4-difluorophenyl)-6-fluoro-7-[(3R)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Synonyms Sources
(+)-temafloxacin ChEBI
(R)-(+)-temafloxacin ChEBI
Registry Number Type Source
4301728 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
1846917 PubMed citation Europe PMC
Last Modified
19 March 2014