CHEBI:31202 - amfenac sodium hydrate

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ChEBI Name amfenac sodium hydrate
ChEBI ID CHEBI:31202
Definition A hydrate that is the monohydrate of the sodium salt of amfenac.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C15H14NNaO4
Net Charge 0
Average Mass 295.26570
Monoisotopic Mass 295.08205
InChI InChI=1S/C15H13NO3.Na.H2O/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10;;/h1-8H,9,16H2,(H,17,18);;1H2/q;+1;/p-1
InChIKey QZNJPJDUBTYMRS-UHFFFAOYSA-M
SMILES O.[Na+].Nc1c(CC([O-])=O)cccc1C(=O)c1ccccc1
Roles Classification
Biological Role(s): cyclooxygenase 2 inhibitor
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
cyclooxygenase 1 inhibitor
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
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ChEBI Ontology
Outgoing amfenac sodium hydrate (CHEBI:31202) has part sodium (2-amino-3-benzoylphenyl)acetate (CHEBI:75918)
amfenac sodium hydrate (CHEBI:31202) has role antipyretic (CHEBI:35493)
amfenac sodium hydrate (CHEBI:31202) has role cyclooxygenase 1 inhibitor (CHEBI:50630)
amfenac sodium hydrate (CHEBI:31202) has role cyclooxygenase 2 inhibitor (CHEBI:50629)
amfenac sodium hydrate (CHEBI:31202) has role non-narcotic analgesic (CHEBI:35481)
amfenac sodium hydrate (CHEBI:31202) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
amfenac sodium hydrate (CHEBI:31202) is a hydrate (CHEBI:35505)
IUPAC Name
sodium (2-amino-3-benzoylphenyl)acetate—water (1/1)
Synonyms Sources
2-amino-3-benzoylbenzeneacetic acid, monosodium salt, monohydrate ChemIDplus
AHR-5850D ChemIDplus
amfenac sodium ChemIDplus
sodium (2-amino-3-benzoylphenyl)acetate monohydrate ChemIDplus
Manual Xref Database
D01788 KEGG DRUG
View more database links
Registry Numbers Types Sources
13313120 Reaxys Registry Number Reaxys
61618-27-7 CAS Registry Number KEGG DRUG
61618-27-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
6471132 PubMed citation Europe PMC
7122676 PubMed citation Europe PMC
8376494 PubMed citation Europe PMC
Last Modified
14 October 2013