CHEBI:3724 - citalopram hydrobromide

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ChEBI Name citalopram hydrobromide
ChEBI ID CHEBI:3724
Definition A racemate comprising equimolar amounts of (R)-citalopram hydrobromide and escitalopram hydrobromide. It is used for the treatment of depression. Only the (S)-enantiomer, (escitalopram hydrobromide) is active.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Biological Role(s): serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
Application(s): antidepressant
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
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ChEBI Ontology
Outgoing citalopram hydrobromide (CHEBI:3724) has part (R)-citalopram hydrobromide (CHEBI:77422)
citalopram hydrobromide (CHEBI:3724) has part escitalopram hydrobromide (CHEBI:77423)
citalopram hydrobromide (CHEBI:3724) has role antidepressant (CHEBI:35469)
citalopram hydrobromide (CHEBI:3724) has role serotonin uptake inhibitor (CHEBI:50949)
citalopram hydrobromide (CHEBI:3724) is a racemate (CHEBI:60911)
IUPAC Name
3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium bromide
Synonyms Sources
1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile monohydrobromide ChemIDplus
1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile monohydrobromide ChemIDplus
1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile monohydrobromide ChemIDplus
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide IUPAC
Brand Name Source
Celexa KEGG DRUG
Manual Xref Database
D00822 KEGG DRUG
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Registry Numbers Types Sources
5368282 Beilstein Registry Number Beilstein
59729-32-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
15739093 PubMed citation Europe PMC
16595940 PubMed citation Europe PMC
17664246 PubMed citation Europe PMC
22992488 PubMed citation Europe PMC
Last Modified
21 February 2014