CHEBI:65964 - gilvusmycin

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ChEBI Name gilvusmycin
ChEBI ID CHEBI:65964
Definition An antibiotic isolated from the culture broth of Streptomyces sp. QM16 with potent cytotoxic activity against the human tumor cells.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C38H34N6O8
Net Charge 0
Average Mass 702.71200
Monoisotopic Mass 702.24381
InChI InChI=1S/C38H34N6O8/c1-15-13-39-29-24(46)11-25-38(26(15)29)12-17(38)14-44(25)37(50)23-10-21-19-6-8-43(31(19)33(48)35(52-4)28(21)41-23)36(49)22-9-20-18-5-7-42(16(2)45)30(18)32(47)34(51-3)27(20)40-22/h9-11,13,17,39-41,47-48H,5-8,12,14H2,1-4H3
InChIKey XUBJLJZOSKJNMY-UHFFFAOYSA-N
SMILES COc1c(O)c2N(CCc2c2cc([nH]c12)C(=O)N1CCc2c1c(O)c(OC)c1[nH]c(cc21)C(=O)N1CC2CC22C1=CC(=O)c1[nH]cc(C)c21)C(C)=O
Metabolite of Species Details
Streptomyces sp. (NCBI:txid1931) of strain QM16 See: PubMed
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing gilvusmycin (CHEBI:65964) has role antimicrobial agent (CHEBI:33281)
gilvusmycin (CHEBI:65964) has role antineoplastic agent (CHEBI:35610)
gilvusmycin (CHEBI:65964) has role metabolite (CHEBI:25212)
gilvusmycin (CHEBI:65964) is a aromatic ether (CHEBI:35618)
gilvusmycin (CHEBI:65964) is a bridged compound (CHEBI:35990)
gilvusmycin (CHEBI:65964) is a cyclic ketone (CHEBI:3992)
gilvusmycin (CHEBI:65964) is a organonitrogen heterocyclic compound (CHEBI:38101)
gilvusmycin (CHEBI:65964) is a phenols (CHEBI:33853)
IUPAC Name
6-({6-[(6-acetyl-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl)carbonyl]-5-hydroxy-4-methoxy-3,6,7,8-tetrahydropyrrolo[3,2-e]indol-2-yl}carbonyl)-3-methyl-4,4a,5,6-tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-8(1H)-one
Registry Number Type Source
8382539 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
10348041 PubMed citation Europe PMC
Last Modified
21 September 2012