CHEBI:465284 - ganciclovir

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ChEBI Name ganciclovir
ChEBI ID CHEBI:465284
Definition An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42659, CHEBI:5273
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Formula C9H13N5O4
Net Charge 0
Average Mass 255.23060
Monoisotopic Mass 255.09675
InChI InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChIKey IRSCQMHQWWYFCW-UHFFFAOYSA-N
SMILES Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing ganciclovir (CHEBI:465284) has functional parent guanine (CHEBI:16235)
ganciclovir (CHEBI:465284) has role antiinfective agent (CHEBI:35441)
ganciclovir (CHEBI:465284) has role antiviral drug (CHEBI:36044)
ganciclovir (CHEBI:465284) is a 2-aminopurines (CHEBI:20702)
ganciclovir (CHEBI:465284) is a oxopurine (CHEBI:25810)
Incoming valganciclovir (CHEBI:63635) has functional parent ganciclovir (CHEBI:465284)
IUPAC Name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one
INN Source
ganciclovir KEGG DRUG
Synonyms Sources
2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol ChEMBL
2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one ChEMBL
2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone ChEMBL
9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine ChemIDplus
9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE PDBeChem
9-[(1,3-dihydroxy-2-propoxy)methyl]guanine ChEMBL
GA2 DrugBank
Ganciclovir KEGG COMPOUND
ganciclovirum ChemIDplus
gancyclovir ChEMBL
Manual Xrefs Databases
1277 DrugCentral
D00333 KEGG DRUG
DB01004 DrugBank
GA2 PDBeChem
Ganciclovir Wikipedia
HMDB0015139 HMDB
LSM-5382 LINCS
US4355032 Patent
View more database links
Registry Numbers Types Sources
3654487 Beilstein Registry Number Beilstein
3654487 Reaxys Registry Number Reaxys
82410-32-0 CAS Registry Number KEGG COMPOUND
82410-32-0 CAS Registry Number DrugBank
82410-32-0 CAS Registry Number KEGG DRUG
82410-32-0 CAS Registry Number ChemIDplus
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Last Modified
22 February 2017