CHEBI:6364 - laminarin

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ChEBI Name laminarin
ChEBI ID CHEBI:6364
Definition A polysaccharide composed of β-(1→3)-linked glucose residues containing sporadic β-(1→6)-linkages as branch points or inter-residue linkages and 2-3% D-mannitol at some reducing termini.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C12H22O11(C6H10O5)n
Metabolite of Species Details
Sargassum fusiforme (NCBI:txid590727) See: PubMed
Eisenia bicyclis (NCBI:txid6395) See: PubMed
Laminaria digitata (NCBI:txid80365) See: PubMed
Roles Classification
Biological Role(s): marine metabolite
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
immunological adjuvant
A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
Application(s): animal growth promotant
Substances that are administered to farmed animals to improve productivity by promoting weight gain, increasing muscle mass, limiting fat deposition, reducing feed consumption, and reducing waste production.
immunological adjuvant
A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing laminarin (CHEBI:6364) has role animal growth promotant (CHEBI:82655)
laminarin (CHEBI:6364) has role apoptosis inducer (CHEBI:68495)
laminarin (CHEBI:6364) has role immunological adjuvant (CHEBI:50847)
laminarin (CHEBI:6364) has role marine metabolite (CHEBI:76507)
laminarin (CHEBI:6364) is a polysaccharide (CHEBI:18154)
Synonyms Sources
algal β-1,3-glucan ChEBI
Laminaran KEGG COMPOUND
Laminarin KEGG COMPOUND
Manual Xrefs Databases
C00771 KEGG COMPOUND
CPD-3602 MetaCyc
Laminarin Wikipedia
View more database links
Registry Numbers Types Sources
10330714 Reaxys Registry Number Reaxys
8187226 Reaxys Registry Number Reaxys
9008-22-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
20096763 PubMed citation Europe PMC
20599236 PubMed citation Europe PMC
24131869 PubMed citation Europe PMC
24274485 PubMed citation Europe PMC
24337571 PubMed citation Europe PMC
24413558 PubMed citation Europe PMC
24502994 PubMed citation Europe PMC
24726062 PubMed citation Europe PMC
24765209 PubMed citation Europe PMC
25147183 PubMed citation Europe PMC
25266890 PubMed citation Europe PMC
25443973 PubMed citation Europe PMC
Last Modified
08 December 2014
General Comments
2011-06-14 Laminarin is found in brown seaweed, particularly the Laminaria species. Laminarin obtained from Laminaria digitata consists of the (major) M-series, containing 20-30 glucosyl residues linked to terminal mannitol, and the (minor) G-series with 22-28 glucosyl residues. There is a 3:1 ratio of M-series to G-series molecules, with an average of 1.3 branches per molecule.
2011-06-14 Laminarin can be sulfated to varying degrees. Highly sulfated laminarin has anticoagulant properties comparable to heparin.