CHEBI:31270 - beraprost sodium

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ChEBI Name beraprost sodium
ChEBI ID CHEBI:31270
Definition The organic sodium salt of beraprost. It is used in the treatment of chronic arterial occlusive disease and primary pulmonary hypertension in Japan.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C24H29O5.Na
Net Charge 0
Average Mass 420.481
Monoisotopic Mass 420.19127
InChI InChI=1S/C24H30O5.Na/c1-3-4-7-15(2)19(25)13-12-17-20(26)14-21-23(17)18-10-5-8-16(24(18)29-21)9-6-11-22(27)28;/h5,8,10,12-13,15,17,19-21,23,25-26H,6-7,9,11,14H2,1-2H3,(H,27,28);/q;+1/p-1/b13-12+;/t15?,17-,19+,20+,21-,23-;/m0./s1
InChIKey YTCZZXIRLARSET-VJRSQJMHSA-M
SMILES [Na+].[H][C@]12C[C@@H](O)[C@]([H])(\C=C\[C@@H](O)C(C)CC#CC)[C@@]1([H])C1=C(O2)C(CCCC([O-])=O)=CC=C1
Roles Classification
Biological Role(s): prostaglandin receptor agonist
An agonist that binds to and activates prostaglandin receptors.
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
vasodilator agent
A drug used to cause dilation of the blood vessels.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing beraprost sodium (CHEBI:31270) has part beraprost(1−) (CHEBI:156557)
beraprost sodium (CHEBI:31270) has role anti-inflammatory agent (CHEBI:67079)
beraprost sodium (CHEBI:31270) has role antihypertensive agent (CHEBI:35674)
beraprost sodium (CHEBI:31270) has role platelet aggregation inhibitor (CHEBI:50427)
beraprost sodium (CHEBI:31270) has role prostaglandin receptor agonist (CHEBI:66900)
beraprost sodium (CHEBI:31270) has role vasodilator agent (CHEBI:35620)
beraprost sodium (CHEBI:31270) is a organic sodium salt (CHEBI:38700)
IUPAC Name
sodium 4-{(1R,2R,3aS,8bS)-2-hydroxy-1-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan-5-yl}butanoate
Synonyms Sources
beraprost Na ChEBI
beraprost sodium KEGG COMPOUND
TRK 100 ChEBI
TRK-100 ChemIDplus
Brand Names Sources
Beracle ChEBI
Berasil ChEBI
Berast ChEBI
Berastolin ChEBI
Berasus LA ChEBI
Careload LA ChEBI
Dorner ChEBI
Procylin KEGG COMPOUND
Prorner ChEBI
Manual Xref Database
D01551 KEGG DRUG
View more database links
Registry Number Type Source
88475-69-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
30 September 2020